Why use a Holistic treatment for Cancer?

It always surprises me to see that so many people still assume the best or only options for cancer are surgery, radiation, and chemotherapy (otherwise known as slash, burn, and poison). I refuse to believe that God put us here to live in fear of dread diseases and to ransom our health back from the medical profession for tens of thousands of dollars. It’s time to get the word out: cancer, like any disease, is not a random misfortune. There are reasons for these things. When you understand the reasons, you can get rid of them.





Conventional medicine considers cancer to be a localized disease of mutated cell growth multiplying
uncontrollably. As this mutated cell growth continues, a tumor or a mass is formed. The normal
process of cell growth, replication, differentiation, and maturation becomes unregulated, leading to
further uncontrolled growth in the body (Walters,1993).


I can agree with most of the above statement except for the idea that the cellular process is only
a localized disease. To me and many in the field of holistic medicine, cancer is not a localized
disease but a systemic disease. As the process of mutated cell growth occurs, a healthy immune
system will recognize this uncontrolled growth and will elicit a response by sending macrophages to the
region for cellular phagocytosis of the mutated cells (Walters, 1993). Also, the immune system promotes
the release of endogenous compounds to inhibit the uncontrolled cell growth (Diamond, 1997). This
process occurs almost daily in healthy humans and animals. It is felt that the disease of cancer is an
immune system deficiency and is an internal systemic disease process with a localized lesion.
Therefore, the treatment for cancer must address the immune system deficiency and the
internal disease process, and not only the localized lesion. 


Conventional medical treatment for cancer does what I call “cut, slash and destroy”. The use of surgery to cut out the local lesion, then use radiation to slash away any leftover local mutated cells, and finally use chemotherapy to destroy any fast
growing cells – which hopefully will include the metastatic cells (Walters, 1993). This entire process
is very suppressive to the immune system, which is at the root of cancer disease.


The holistic treatment for cancer should focus on immune system stimulation, correction of the
internal disease process, and destruction of the mutated cellular growth with natural nontoxic
compounds.



Diet
I would like to thank Dr. Gregory Ogilvie (1995)
from Colorado State University School of Veterinary
Medicine for researching to determine the proper diet
for the cancer patient. In simple terms, the best diet
is; low carbohydrates, moderate fats, and high
quality proteins.



Omega 3 Fatty Acids.
These products may be made with flaxseed oil or fish oils. These
oils can have beneficial effects on the heart,
cancer, diabetes, arthritis, skin, and most
important, they slow down the cachexia
(wasting disease) of the cancer patient
(Ogilvie, 1995). The dose may vary because
of digestive sensitivity. They say try to get to 250 mg
of Omega 3 per 20 lbs. per day or higher at least.



Anti-Angiogenesis. 
This is the biggest word in cancer therapy today. Every
pharmaceutical company is trying to make
a product to inhibit angiogenesis.
Angiogenesis is the process of the production
of new blood vessels. This is what allows the
cancer mass to grow. When the mutated cell
growth begins, there are two things that
happen: 1) hypoxia to the surrounding cells,
and 2) inhibited cellular nutritional uptake.
The surrounding cells to the cancer are
starving for food and oxygen. So the body
recognizes this by cellular communication
and starts to send out new micro-blood
vessels to the region. This only aids the
cancer to continue to grow faster and larger.
Anti-angiogenesis will inhibit the growth of
these new blood vessels and inhibit the
growth of the cancer (Boik, 2001; Diamond,
1997). 


There are a few that I use.



Natural products that would be used to treat cancer
must inhibit these seven pro-cancer events. The
actions that inhibit the seven pro-cancer events are:
1. Reduce Genetic Instability
2. Inhibit Abnormal Expression of Genes
3. Inhibit Abnormal Signal Transduction
4. Encourage Normal Cell-to-Cell
Communication
5. Inhibit Tumor Angiogenesis
6. Inhibit Invasion and Metastasis
7. Increase the Immune Response





Here are a just few I use:
Resverstrol – Stilbene from grapes and wine
which acts as an antioxidant, inhibits platelet
aggregation, inhibits 6 of the 7 pro-cancer
events, inhibits insulin resistance, and
inhibits abnormal estrogen action (Boik,
2001; Neilson, 2000).
Turmeric Extract – The extract is curcumin,
which acts as an antioxidant, strong antiinflammatory
effect, inhibits insulin
resistance, inhibits cancer cellular
proliferation, inhibits metastasis, inhibits 5
of the 7 pro-cancer events (Arbiser, 1998;
Boik, 2001; Dorai, 2000) .
Green Tea Extract (GTE) – A group of
flavonoids that acts as an antioxidant;
inhibits 6 of the 7 pro-cancer events; and has
in-vitro and in-vivo anticancer activity (Boik,
2001; Lyn-Cook, 1999; Sabzuka, 2000).





There are many single herbal and small formula
products that are used to kill cancer cells such as:




Artemisinin
this is an extract of Wormwood. 



Certain Mushroom Formulas
Very useful for immune
enhancing, energy boosting.





I try to place as many of the supplement products into my dog Lucy's food as
possible, for ease of administration. I use diet changes, supplements, immune enhancing herbal
products all at the same time. I feel the window of treatment for success is very short and to place the cancer into
remission requires aggressive therapy, so I throw the every protocol I can find at her cancer. The supplements are
started at low levels and increase slowly once the digestion system adjusted to the changes.



It is recommended no vaccines in cancer patients. Exercise the patient as much as possible.
It has been recommended to discontinue monthly flea and tick treatment, if these products
are being used. Pest control for the house should be discontinued, especially in the beginning of the
case. Any emotional, mental, and physical stress to the cancer patient will reduce the chances of success
in the holistic cancer treatment.




For a full list of what I use to give to Lucy


Why use a Holistic treatment for Cancer? Because Lucy went into remission using this method and still is. She is well beyond what vets told us what her expected life would be. With full quality of life.

Astragalus and Cancer

Other herbs that bear mentioning include Astragalus, which has the action of enhancing cellular and humoral immunity. Considered a superior tonic root in Chinese medicine, Astragalus strengthens the body’s resistance and invigorates and promotes tissue regeneration. As a non-specific immunostimulant and protector of adrenal cortical function, it shows promise for cancer patients undergoing radiation and chemotherapy as well as environmental allergies. Codonopsis is one of the most famous and widely used Chinese tonic herbs. It is rich in immune stimulating polysaccharides which are beneficial to people with cancer as well as those who are healthy. These polysaccharides have been shown to be useful in supporting the immune systems of people with cancer who are using the herbs in conjunction with conventional cancer therapies. Codonopsis has been demonstrated to have radiation protection activity and can be effective in protecting cancer patients receiving radiation therapy from the side effects without diminishing the benefits of the therapy. Codonopsis also has an interferon-inducing activity that may be of importance in many immune deficiency conditions, including HIV infection.

Overview of Adaptogens for Cancer from Around the World

 An Overview of Adaptogens for Cancer from Around the World


The idea of using tonic remedies to restore balance and health in a person is an ancient idea. The word
and concept of an “adaptogen” is a relatively new way of describing a type of remedy commonly
found in traditional Chinese (Qi tonic), African (Manyasi), Tibetan, Ayurvedic (Rasayana), and
Cherokee medicine. The actual word adaptogen was first used by a Soviet scientist, Dr. Nikolai
Lazarev, who under grants from the military, was researching substances which produced a “state of
nonspecific resistance (SNIR)11”. The idea was to find ways to enhance the productivity and
performance of soldiers, athletes, and workers without using dangerous stimulants. Much of the early
research into adaptogens was done by Dr. I.I. Brekhman who, in the late 1950’s, studied Panax
ginseng. Looking for a less expensive and more available substitute, he changed his focus to a native
Russian shrub, Eleutherococcus senticosis. His first monograph of this now popular herb (Siberian
Ginseng, Eleuthero) was published in 1960.


In 1969 Brekhman and Dardymov defined the general pharmacological properties of adaptogenic
substances. These include:


a.) The substance is relatively non-toxic to the recipient.
b.) An adaptogen has “non-specific” activity and acts by increasing resistance of the organism
to a broad spectrum of adverse biological, chemical, and physical factors.
c.) These substances tend to help regulate or normalize organ and system function within the
organism.
Several theories have been suggested to explain the effects of adaptogenic substances. One theory
proposed by Dardymov and Kirkorian9 argues that adaptogens function primarily due to their
antioxidant and free radical scavenging effects. While their theory is partially accurate, it is inadequate
to explain the full effects of these medicinals.


More recent research postulates that adaptogens work primarily by affecting the Hypothalamic/
Pituitary/Adrenal (HPA) axis and the Sympathoadrenal System (SAS)9. Thus, adaptogens modulate
our response to stress (physical, environmental, or emotional) and help regulate the interconnected
endocrine, immune, and nervous systems. This re-regulation of a disordered or highly stressed system
is achieved by metabolic regulators such as cytokines, catecholamines, glucocorticoids, cortisol,
serotonin, nitric oxide (NO), cholecystokinin, corticotrophin-releasing factor (CRF), and sex
hormones. This broad array of biochemical activators helps explain why adaptogens also have antiinflammatory,
antioxidant, anxiolytic, antidepressant, nervine, and amphoteric effects as well. So
while most or all adaptogens are antioxidants, having antioxidant properties (Green Tea, Rosemary,
Cranberry) is not enough to make a substance an adaptogen. Brekhman and Dardymov’s list
of physiological actions of adaptogens states that adaptogens help modulate system function and
maintain homeostasis. So all adaptogens act as broad spectrum amphoterics to living organisms, but
they rarely have a pronounced effect on only one specific organ or system.




Adaptogenic Materia Medica for humans
WARNING: I HAVE NOT REVIEWED THIS LIST FOR DOG AND PET USAGE YET. 
HOWEVER I DO USE SOME OF THESE ON MY DOG SUCH AS RED GINSENG, LICORICE ROOT, Huang Qi (Astragalus),  Ashwagandha, AND ALL FUNGUS/MUSHROOMS LISTED.


1. Well-known adaptogens:


Chinese or Korean Ginseng root (Panax ginseng)


Red Ginseng root– Sweet, slightly bitter, warm-hot, moist


White Ginseng root– Sweet, bitter, warm, moist


Western Classification: Adaptogen, antioxidant, antiinflammatory, antiasthmatic, cardiotonic, CNS
stimulant (mild), immune amphoteric.


Ginseng, especially Red Ginseng, is the most stimulating of the adaptogens. Traditionally it is used in
Chinese medicine for older men with deficient kidney yang (impotence, fatigue, BPH, low back pain)
or for patients with vanquished qi (CFIDS, CHF). It is a useful part of a protocol for deficient
depression, exhaustion, Addison’s Disease (with Licorice), deficient insomnia, diabetes, cachexia,
immune deficiency allergic asthma (use with Schisandra and Licorice), erectile dysfunction, and it
helps prevent or treat leucopenia in patients receiving chemotherapy or radiation for cancer. Recent
human studies using Asian Ginseng showed it reduced symptoms of COPD5, improved survival times
in patients with gastric cancer, and reduced incidence of metastases14. Overuse of Ginseng in yang
(excess) people can cause insomnia, anxiety, increased blood pressure, and irritability.


American Ginseng root (Panax quinquefolius) – Bitter, slightly sweet, warm, moist
Western Classification: Adaptogen, antioxidant, antiinflammatory, bitter tonic, immune amphoteric.
American Ginseng is less stimulating/heating than Panax ginseng; making it more appropriate for
regular use by younger people of both sexes. It is still of a warming (nourishing) nature and is
appropriate for fatigue, recovery from pneumonia or bronchitis (especially with a dry cough), CFIDS,
asthma, chronic stress with depression or anxiety, and autoimmune diseases of the lungs or GI tract. I
find it of great benefit for jet lag, metabolic syndrome, adrenal deficiency, immune depletion, sexual
neurasthenia, and deficient insomnia. It is much less likely to over stimulate people than is Asian
Ginseng and it is better for yin deficiency conditions (dryness)17.


Eleuthero root (Eleutherococcus senticosis) - Sweet, slightly bitter, neutral
Western Classification: Adaptogen, anticholesteremic, antioxidant, antiinflammatory (mild), immune
potentiator, nervine.
Eleuthero (formerly Siberian Ginseng) is less tonifying than the true Ginsengs (Panax spp.). It is
neutral energetically and so is appropriate for daily use. It is indicated for the “average” American
who is overstressed, undernourished but overfed, doesn’t get enough sleep or exercise, has dark circles
under his or her eyes, a quivering tongue, and contracting/dilating pupils. This description of HPA
axis depletion without overt pathology is precisely where Eleuthero is useful. Taken regularly it
enhances immune function, reduces cortisol levels and inflammatory response, and it promotes
improved cognitive and physical performance. In human studies Eleuthero has been successfully used
to treat bone marrow suppression caused by chemotherapy or radiation, angina, hypercholesterolemia,
and neurasthenia with headache, insomnia, and poor appetite3,6.


Wu Wei Zi berries/seeds (Schisandra chinensis, S. splenathera) – Sour, pungent, warm, dry
Western Classification: Adaptogen, antioxidant, antiinflammatory, astringent, antiasthmatic,
hepatoprotective, immune amphoteric.
Schisandra berries mildly stimulate CNS activity and can be used with Prince Seng for neurasthenia
and exhaustion. It is very useful as part of a protocol for hepatitis B&C (use with Milk Thistle and
Turmeric), asthma (with Licorice), and for nervous system disorders including Parkinson’s disease,
Meniere’s syndrome, deficient depression, and adult ADHD. Wu Wei Zi is used in Fu Zheng therapy
to support immune function and prevent side effects caused by cancer chemotherapy.
Traditionally, this herb is used to astringe a leaky jing gate (urinary incontinence, leucorrhea, diarrhea,
and spermatorrhea) and to reduce excessive sweating.


Dang Shen root (Codonopsis pilosula) – Sweet, warm, moist
Western Classification: Adaptogen, gastroprotective, hypoglycemic agent, immune potentiator, nervine
Codonopsis, also known as “poor man’s ginseng” is used in TCM as a mild substitute for Panax. It
is a spleen qi tonic and is used for poor appetite, gastric irritation, and/or ulcers, fatigue, and weak
limbs. It is also a lung qi tonic and can be used for shortness of breath with a dry cough and frequent
respiratory tract infections (use with Prince Seng). Dang Shen is commonly used to strengthen the
immune system (cancer, HIV, mononucleosis) and is frequently used in Fu Zheng therapies to prevent
side effects from chemotherapy or radiation. It increases hemoglobin levels and the number of red
blood cells as well.


Licorice rhizome ROOT (Glycyrrhiza glabra, G. uralensis) – Sweet, slightly bitter, warm, moist
Western Classification: Adaptogen, antihistamine, antiinflammatory, antidiuretic, antioxidant,
antitussive, antiviral, demulcent, hepatoprotective, immune amphoteric, gastroprotective.
Gan Cao (Licorice) is a versatile and commonly used herb in TCM, Unani-Tibb and European
herbal traditions. It is an immune amphoteric and can be useful for autoimmune disorders (Lupus,
Scleroderma, Crohn’s disease, R.A.) as well as immune deficiency conditions (cancer, HIV, CFIDS). It
strengthens adrenal function and can be used with Panax ginseng for Addison’s disease. It is also
useful for allergies, ulcers, elevated cortisol levels, PCOS (with Serenoa and Paeonia), and spasmodic
coughs. Excess doses of Licorice can have a hyperaldosterogenic effect (increased retention of sodium
and excretion of potassium). Women are more sensitive to this effect than men and patients with
hypertension should avoid using this herb on a continual basis.


Ashwagandha root (Withania somnifera) – Bitter, sweet, warm, dry
Western Classification: Adaptogen, antiinflammatory, antioxidant, antispasmodic, astringent, immune
amphoteric, sedative (mild).
This herb is one of the Rasayana (rejuvenative) herbs of Ayurveda. It is one of the few calming
adaptogens and has traditionally been used for anxiety, bad dreams, mild OCD, insomnia, and nervous
exhaustion. It acts as an antispasmodic & antiinflammatory and is very useful for fibromyalgia (with
Kava and Scullcap), restless leg syndrome, mild Tourette’s syndrome, and osteo-arthritis. It is an
immune amphoteric useful for hyper- and hypo-immune conditions. I find it especially useful for
autoimmune conditions affecting the muscles and joints such as rheumatoid arthritis, Ankylosing
Spondylitis, polymyositis, and polymyalgia rheumatica (PMR). It enhances male fertility (sperm count
and sperm motility) and, due to its iron content, it benefits iron-deficient anemia. Ashwagandha also
stimulates thyroid function. Studies in mice showed significant increases of serum T3(18%) and
T4(111%) after 20 days of use8.


Cordyceps fungus (Cordyceps sinensis) – Sweet, slightly acrid, warm, moist
Western Classification: Adaptogen, antiasthmatic, antileukemic, antioxidant, hepatoprotective,
immune potentiator, nephroprotective, sedative (mild).
The caterpillar fungus (winter insect, summer plant) is one of the more unusual adaptogens. While
the parasitized larvae are still available, most Cordyceps is now grown on soybeans. It is used in TCM
for deficient kidney yin and yang caused by chronic disease or extremely rigorous labor/athletic
training. It improves libido and sperm count, relieves fatigue, anemia, chronic coughs, and bone
marrow (erythroid) suppression due to radiation therapy.
Cordyceps also has active antitumor and antileukemic activity (use with Panax notoginseng), it
enhances circulation and cardiac output, as well as lung capacity. Cordyceps combined with Nettle
Seed and Unprocessed Rehmannia is very useful for treating degenerative kidney disease. In human
studies Cordyceps has shown significant benefit for male sexual dysfunction, hyperlipidemia, low
platelet counts, allergic rhinitis, tinnitus, and chronic tracheitis3.


New Adaptogens
Holy Basil herb (Ocimum sanctum) – Pungent, sweet, warm, neutral
Western Classification: Adaptogen, antibacterial, anticholesteremic, antidepressant, antioxidant,
antiviral, carminative, expectorant, immune amphoteric.
Tulsi, or Holy Basil, has a long tradition of use in Ayurvedic, Siddha, and the Unani-Tibb systems
of medicine. It is considered a Rasayana or rejuvenative medicine and is traditionally used to improve
memory, to treat coughs, colds, indigestion, asthma (with Black Pepper), and fatigue. More recent
research has shown it reduces excess immune response in allergic asthma and allergies while
enhancing normal immune function. In addition, in animal studies, it increases endurance, inhibits
ulcer formation, and protects against gamma radiation. In a human trial, Tulsi showed benefits in
NIDDM, reducing fasting blood glucose (17.6%) and postprandial blood glucose (7.3%)12.


Rhodiola root (Rhodiola rosea, R. crenulata) – Sweet, slightly bitter, cool, neutral
Western Classification: Adaptogen, antiinflammatory, antioxidant, antidepressant, cardioprotective,
immune potentiator, nervine.
Known as Rose Root, Golden Root, or Arctic Root, Rhodiola has a long history of use in
Scandinavia, Eastern Europe, and Russia as a rejuvenative tonic. Rhodiola has been an official
medicine in the Soviet Union (now Russia) since 1969, as a mild CNS stimulant, memory enhancer,
cardiotonic, and immune tonic2. In human studies, this root has been shown to be effective for treating
mild depression, neurasthenia, nervous palpitations, impaired cognitive function4, ADD, CFIDS,
erectile dysfunction, amenorrhea, and infertility in women. Due to its cooling nature, Rhodiola is very
useful for patients with excess constitutions with hypertension, liver fire rising headaches, and yang
insomnia. Traditionally, Rhodiola is used in Tibetan medicine for nourishing the lungs, to increase
blood circulation, and for fatigue, altitude sickness, and weakness.


Amla fruit (Emblica officinalis) – Sour, sweet, cool, dry
Western Classification: Adaptogen, antioxidant, anticholesteremic, antiinflammatory, astringent,
radioprotective, thyroxin inhibitor, diuretic, hepatoprotective (mild), nutritive.
Amla, or Amalaki, is a Rasayana or rejuvenative remedy used in Ayurvedic medicine. A 1999
animal study by N.N. Rege concluded that Amla was not only a useful antioxidant and
antiinflammatory, but had adaptogenic activity as well. The extract was shown to protect against
biological, physical, and chemical stressors12. Amla is used clinically for connective tissue disorders
(Scleroderma, R.A., Lupus, Ankylosing Spondylitis), to build blood (anemia – use with
Ashwagandha), and strengthen bones, capillaries, and the eyes. It also inhibits atherosclerosis,
carcinogenesis, and may help slow the degeneration caused by Alzheimer’s disease.


Bryonia root (Bryonia alba) – Bitter, cold, dry
Western Classification: Adaptogen, antiinflammatory, analgesic/antibacterial, antioxidant, cardiotonic,
immune amphoteric.
Usually thought of as a highly toxic plant, Bryonia root has been found to be both an adaptogen and
non-toxic if gathered in the spring or autumn.
The summer gathered roots have a very different chemistry and are, as commonly thought, quite toxic.
Bryonia (commercially known as Lostak) is available as a tonic remedy in Russia and Eastern Europe.
It is used to prevent radiation-induced cell damage, side effects from chemotherapy, treat CFIDS, and
it improves physical endurance and work capacity10.


Aralia manshurica, A. elata, A. schmidtii roots – Pungent, warm, moist
Western Classification: Adaptogen, antioxidant, CNS stimulant (mild), expectorant, hypoglycemic
agent, nephroprotective.
These three Aralia spp. (Araliaceae) are native to Siberia and Manchuria, and are used in Russia as
mild adaptogenic tonics. Aralia elata is the most researched of the three, and in animal studies it
protected mice against radiation damage16. Readers should be aware that not all Aralia spp. have
adaptogenic activity (Ex: A. racemosa, A. spinosa).


Jiaogulan herb (Gynostemma pentaphylla) – Sweet, slightly bitter, neutral
Western Classification: Adaptogen, antioxidant, expectorant, hypocholesteremic, hepatoprotective,
immune potentiator, nervine.
This member of the Curcubitaceae family has a long history of use in Southern China & Taiwan as
a folk remedy for fatigue, weakness, asthma, hepatitis, migraines, and cancer. Due to its low cost and
safety, it has become much more widely used as a “Ginseng” substitute and adaptogen throughout
Southeast Asia. Interestingly, some of the active constituents, gypenosides, are chemically identical to
ginsenosides found in the unrelated Panax species. Clinically, Jiaogulan is useful for hypertension,
congestive heart failure, liver disease, elevated blood lipids, and to strengthen the immune system and
inhibit cancer1.


Guduchi stem (Tinospora cordifolia) – Bitter, warm, dry
Western Classification: Adaptogen, antiinflammatory, antioxidant, hepatoprotective, diuretic, immune
amphoteric.
Guduchi is another of the Ayurvedic Rayana remedies. It is traditionally used for impotence, gout,
edema, arthritis, and general weakness. Human and animal studies have shown it increases uric acid
excretion, is a powerful antiinflammatory for arthralgias, acts as an immunomodulator (useful for
cancer patients undergoing chemotherapy), hepatoprotective agent (hepatitis B&C), and it reduces
elevated blood sugar levels.


Little-Known Adaptogens
Oplopanax elatus /Echinopanax elatus bark– Korean Araliaceae
This herb has been reported to have adaptogenic and antioxidant qualities in Russian literature.
Trichopus zeylanicus seed
Is used by the Kani tribe of India for energy, to increase stamina, and to promote immunity and
vitality. It has been shown in animal studies to increase adrenal corticosterone levels, act as a
hepatoprotective agent, and an aphrodisiac13.


Hoppea dichotoma root
An Ayurvedic plant traditionally used as a nerve tonic. It has been reported in the literature to have
adaptogenic properties.


Rhaponticum carthamoides root/Leuzea carthamoides
A Russian herb used as a CNS stimulant and as a restorative agent to the nervous system. Animal
studies have shown immunostimulant, antitumor, and cognitive enhancing effects.


Shalajit-bitumenous pitch – Bitter, slightly pungent, warm
An Ayurvedic mineral remedy used to enhance immune function and tonify the heart, liver, and
kidneys. It is hepatoprotective, antiinflammatory, antihistamine, and gastroprotective. It is used
clinically to treat diabetes, hepatitis, constipation, digestive disorders, cancer, degenerative kidney
disease (use with Cordyceps), and anemia.


Possible Adaptogens


Mimosa flowers or stem bark (Albizzia julibrissin) – Sweet, neutral
Western Classification: Mild adaptogen (?), antidepressant, antioxidant, anxiolytic, nervine.
Japanese researchers have suggested Albizzia has adaptogenic effects. There is little data to support
this statement, but the flowers and bark of this small, shrubby tree are superb mood-elevators and I use
it with Hawthorn and Rose petals to treat “broken hearts”. In TCM the bark (and flowers) are used for
emotional problems caused by liver qi stagnation – short temper, depression, irritability, impaired
memory, and PMS/menopausal mood swings3.


Saw Palmetto berries (Serenoa repens) – Acrid, sweet, warm, moist
Western Classification: Mild adaptogen (?), antiinflammatory, diuretic, expectorant, immune
potentiator, nutritive.
Saw Palmetto is thought of as a “prostate herb”, but in reality it is much more. When it was
introduced into Western medical practice in 1877 it was used for cachexia, neurasthenia, anorexia, and
general depletion. From a TCM standpoint, it is a tonic to the kidney yin, lung, and spleen. These
qualities are consistent with most, if not all, Chinese adaptogenic remedies. I use it in practice for
asthenic, deficient patients who are underweight, have difficulty breathing, and have dry hair and
skin17.


Eucommia bark (Eucommia ulmoides) – Sweet, slightly pungent, warm, neutral
Western Classification: Mild adaptogen (?), antiinflammatory, antioxidant, antispasmodic, diuretic,
gastroprotective, hypotensive.
Japanese research suggests Du Zhong, Eucommia bark or leaves, have adaptogenic effects.
Traditionally, it is used for hypertension, deficient kidney yang (low back pain, impotence),
strengthening bones, ligaments, and muscles, and preventing miscarriage. Recent data indicates this
herb promotes collagen synthesis, protects against gastric ulcers, and relieves stress and hypertension.
It also lowers LDL & VLDL cholesterol levels and increases phagocyte activity3,19.


Suma bark (Pfaffia paniculata) – Acrid, sweet, neutral
Western Classification: Mild adaptogen (?), antitumor, anticholesteremic, immune potentiator.
Incorrectly called “Brazilian Ginseng”, Pfaffia is reported to have a long history of ethnobotanical
use. Modern phytochemical studies were initiated in Japan in the 1980’s and among the constituents
identified is Ecdysone. This substance is a type of biologically active phytosterol that mimics insect
hormones and is of great interest to researchers. Clinically, Suma has been used to regulate hormones
(Diabetes, BPH, menopausal symptoms), enhance immunity, and inhibit tumor growth.


Reishi fungus (Ganoderma lucidum) – Bitter, warm, neutral
Western Classification: Mild adaptogen (?), anticholesteremic, antiinflammatory, antioxidant,
cardiotonic, immune amphoteric, nervine.
Known in TCM as Ling Zhi, the mushroom of immortality, there is no question that this herb is a
powerful tonic remedy. Whether it affects the HPA axis and SAS are yet to be determined. It is an
important immune amphoteric useful for hypo-(HIV, cancer, CFIDS) or hyper-(allergy, autoimmune
disease) immune disorders. It acts as a calming nervine, mildly lowers blood pressure, relieves angina
pain, and protects the liver against chemical or viral insult. It is an important part of most Fu Zheng
formulas, used in China to enhance chemotherapy and reduce side effects of cancer treatment. In
clinical studies Ganoderma has been effective for treating asthma, hyperlipidemia, leucopenia, anxiety,
and angina3.


Shatavari (Asparagus racemosus) – Sweet, bitter, warm, moist
Western Classification: Mild adaptogen (?), antispasmodic, antitussive, gastroprotective,
aphrodisiac(?), demulcent, diuretic, immune potentiator.
This Indian species of Asparagus is used as a Rasayana remedy in Ayurveda. It has long been used
as a tonic remedy, especially for women, promoting fertility and reducing menopausal symptoms. It is
also used for dry coughs, to heal or prevent gastric ulcers, as a nutritive tonic for cachexia, and as a
soothing diuretic. Recent research indicates Shatavari enhances immune function, increases
corticosteroid production, and promotes cell regeneration12.


Prince Seng root (Pseudostellaria heterophylla) – Sweet, slightly bitter, warm, moist
Western Classification: Mild adaptogen (?), demulcent, immune potentiator, pectoral.
Known in TCM as Tai Zi Shen (or Hai Er Shen), Prince Seng is often referred to as “Ginseng of the
Lungs”. It is a very important lung yin tonic for dry coughs, emphysema, lung damage, or hot/dry lung
conditions. It mildly stimulates the immune system and has been used to treat malaise, neurasthenia,
CFS (use with Schisandra), IBS, and asthma. It is a useful remedy for deficient, sensitive paients who
need tonics, but get easily over stimulated by stronger adaptogens3.


Huang Qi (Astragalus membranaceus) - Sweet, warm, moist
Western Classification: Mild adaptogen (?), antidiaphoretic, antioxidant, antitumor, hepatoprotective,
immune potentiator.
Astragalus is a major tonic remedy in TCM. It is traditionally used for organ prolapse (spleen qi
tonic), to strengthen the Wei qi, modulate sweating, and promote the draining of abscesses. It is a
potent immunostimulant and antitumor agent that has been shown to increase survival time in patients
with adenocarcinoma, non-small cell lung cancer, and breast cancer (use with Ligustrum fruit). It is
also very useful for immune deficiency conditions such as HIV, CFIDS, and TB and in human studies
it helped to prevent colds and influenza. It is a lung qi tonic – for dry coughs, frequent upper
respiratory tract infections, asthma, as well as a cardiotonic (CHF, angina), and it protects the kidneys
against nephrotoxic medications. The combination of Huang Qi and Shan Yao (Dioscorea opposita) is
used in China for type II diabetes with qi and yin deficiency3.






Bibliography
1Blumart, M., Jialiu, L., Jiaogulan, China’s “Immortality” Herb, Torchlight Pub., 1999
2Brown, R.P., Gerarg, P., Ramazanov, Z., Rhodiola rosea, A Phytomedical Overview, Herbalgram
56:40-52, 2002
3Chen, J.K., Chen, T.T., Chinese Medical Herbology and Pharmacology, Art of Medicine Press, City
of Industry, CA, 2004
4Dorbinyan, V., Kteyan, A., et al, Rhodiola rosea in Stress-Induced Fatigue-A Double-Blind Cross-
Over Study of a Standardized Extract SHR-5 With a Repeated Low-Dose Regimen on the Mental
Performance of Healthy Physicians During Night Duty. Phytomedicine: 7(5):365-372, 2000
5Gross, D., Shenkman, Z., et al, Ginseng Improves Pulmonary Functions and Exercise Capacity in
Patients With COPD, Monaldi Arch Chest Dis, 57 (5-6), 242-246, 2002
6Halstead, B. & Hood, L., Eleutherococcus senticosis – Siberian Ginseng, OHAI, 1984
7Klein, R., Kindscher, K., Botanical Medicines With Stress Adaptogen Properties in the Ethnobotanical
Literature: A Review-Unpublished Manuscript 6/21/03
8Panda, S., Kar, A., Changes In Thyroid Hormone Concentrations After Administration of
Ashwagandha Root Extract To Adult Male Mice, Jrl. Pharm. Pharmacol, 1998, 50:1065-1068
9Panossian, A., Adaptogens, Tonic Herbs for Fatigue and Stress, Alternative & Complementary
Therapies, 9(6):327-331, 2003
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Phytomedicine: 4(1): 85-99, 1997.
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Concepts On Their Mode of Action, Phytomedicine: 6(4):287-299, 1999
12Rege, N.N., Thatte, U.M., Dahanukar, S.A., Adaptogenic Properties of Six Rasayana Herbs Used in
Ayurvedic Medicine, Phytotherapy Research: 13(4):275-91, 1999
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From The Alcoholic Extract Trichopus zeylanicus, Gaertn., Phytomedicine: 8(4):283-291, 2001
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Patients With Stage III Gastric Cancer, Am. Jrl. Chin. Med., 30(4):483:494, 2002
15Wagner, H., Immunostimulants and Adaptogens From Plants, pp. 1-18, In Arnason, J., et al,
Phytochemistry of Medicinal Plants, Plenum Press, NY, 1995
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19You-Ping Zhu, Chinese Materia Medica, Chemistry, Pharmacology, and Applications, Harwood,
Amsterdam, 1998





WARNING: I HAVE NOT REVIEWED THIS LIST FOR DOG AND PET USAGE YET. 
HOWEVER I DO USE SOME OF THESE ON MY DOG SUCH AS RED GINSENG, LICORICE ROOT, Huang Qi (Astragalus),  Ashwagandha, AND ALL FUNGUS/MUSHROOMS LISTED.

Melatonin Anti - Cancer Mechanisms

Melatonin Anti - Cancer Mechanisms


Melatonin can kill directly many different types of human tumor cells.  It is a naturally produced cytotoxin, which can induce tumor cell death (apoptosis).  In instances where the tumor has already established itself in the body, melatonin has been shown to inhibit the tumor’s growth rate.  Melatonin exhibits natural oncostatic activity and inhibits cancer cell growth.  In patients in whom cancer already has become a noticeable physical burden and produces overt symptoms, melatonin has been shown to alleviate numerous cancer symptoms  and to inhibit development of new tumor blood vessels (tumor angiogenesis),  which in turn inhibits the cancer from spreading further (metastasis).  Melatonin can retard tumor metabolism and development by lowering the body temperature;  it is a natural inducer of hypothermia. Furthermore, as an inducer of antioxidants  and itself a weak preventive antioxidant,  melatonin hinders tumor cells from participating in free radical damage to normal cells and consequently limits oxidative damage to DNA,  lipids,  amino acids, and proteins. 


In the unfortunate circumstance in which cancer has already overwhelmed the body’s innate cancer-fighting capabilities, including the anti-cancer activity of naturally produced melatonin (levels of which are reduced in most cancer patients), supplemental melatonin may be beneficial.  Melatonin plays a critical role in the host defense system against cancer’s progression by activating the cytokine system,  which exerts growth-inhibiting properties,  and by stimulating the cytotoxic activity of macrophages and monocytes. 



These days, most people are likely to associate melatonin with a hormone that helps people sleep better or prevents jet lag.  Few people realize that melatonin is a cancer-killing hormone  that can enhance the human immune system,  protect against the toxic side effects of chemotherapy  and radiation therapy,   and improve wound healing after cancer surgery.  Even fewer are aware of tons of ongoing clinical trials in which melatonin is being used to help cancer patients better manage their disease symptoms,  improve their quality of life, and even increase their survival rates. 


Although the evidence demonstrating melatonin’s anti-cancer effects  cannot be overstated, melatonin’s impact on cancer treatment remains largely unappreciated. This is likely because pharmaceutical companies have little to gain by advertising the anticancer efficacy of melatonin. In Europe, where melatonin is not even readily available, many clinical trials of melatonin have been conducted.  US pharmaceutical companies, however, have shown little interest in even hosting, let alone funding, such critically important and potentially lifesaving clinical trials.



Administration of supplemental melatonin has been shown to be beneficial even in the supportive care of advanced and end-stage cancer patients: it lessens tissue wasting and diminishes weight loss, fatigue, weakness, and depression; enhances immune function;  improves wound healing;   and improves quality of life and survival rates.  Furthermore, melatonin improves common symptoms found in both patients with advanced cancer and those undergoing chemotherapy; it counteracts anemia  and lymphocytopenia,  stimulates platelet production,  enhances appetite,  and diminishes cancer pain  (including bone pain) through its natural analgesic properties.  These are substantial benefits considering that approximately half of all patients diagnosed with cancer die just because of poor symptom management. 


It can also help combat some of the side effects of chemotherapy and radiation therapy, when given in high doses (one person was advised by a cancer specialist to give her 120-lb dog 20-40 mg each night at bedtime while undergoing radiation treatment).. Melatonin has been used with dogs to combat thunderstorm phobias and certain forms of alopecia (hair loss), and is being tried as a treatment for separation anxiety, so it is safe to use with dogs, at least in moderation.

http://www.ncbi.nlm.nih.gov/pubmed/16207291

http://www.ncbi.nlm.nih.gov/pubmed/12823608


I GIVE LUCY 10MG ON THE NIGHTS SHE DOES NOT TAKE WORMWOOD/Artemisinin. Why alternating weeks? You can't give a strong antioxident like melatonin with wormwood. It would cancel out the wormwood/artemisinin.

New Cancer Protocols - Rotating Treatments

One exciting technique that is used by several herbalists who treat cancer, is that of rotating herbs frequently. The herbalist that developed this unique method of treating cancer is veteran herbalist and ethnobotanist David Winston. Winston is a renowned herbalist who lectures all over the world. He is the author of several books and has over 25 years of clinical herbal experience. According to Winston, his clinical success with cancer clients was greatly enhanced through the practice of continually rotating his formulas each month. 

Because cancer cells duplicate so quickly, the possibility that cancer cells will become acclimated to any drug or herb is quite high. Winston has observed that by rotating their herbal preparations on a monthly basis (this would be shorter in dogs), his clients continue to remain cancer free for a longer period of time. Winston theorizes that by using this method, the cancer cells are not given an opportunity to mutate and become resistant to any single herbal formula. The method seems to hold great promise. Whereas previously, his clients usually went into remission for 18 months to two years, Winston says he now has many clients that have been cancer-free for four to five years.

Ok, so what do we need to rotate? 

No one knows exactly for sure. This is new, but it makes sense. Not sure if you should rotate anti-oxidents or immune boosting herbs. I can see, and I do this, actually rotate Wormwood/Artemisinin to week on/week off. That stuff is neither immune boosting or an anti-oxident, it actually works on killing cancer cells directly.  I would consider rotating some prescription drugs also maybe week on week off or alternating days? Like Doxycycline and Meloxicam/Peroxicam. Or Prednisone alternating with previous. This is all unknown. A dogs week off is 7 weeks to our human timelines.

Ashwagandha herbs effect on Cancer

Ashwagandha herbs effect on Cancer




Antioxidant properties
Researchers from Banaras Hindu University in Varanasi, India, have discovered that some of its chemicals are powerful antioxidants. They tested these compounds for their effects on rat brain and found an increase in the levels of three natural antioxidants — superoxide dismutase, catalase and glutathione peroxidase. They say, "These findings are consistent with the therapeutic use of ashwagandha as an Ayurvedic rasayana (health promoter). The antioxidant effect of active principles may explain, at least in part, the reported anti-stress, cognition-facilitating, anti-inflammatory and anti-aging effects produced by them in experimental animals, and in clinical situations."


Anti-anxiety herb
The roots of ashwagandha are used extensively in Ayurveda, the classical Indian system of medicine. In rodent studies the herb has been shown to reduce anxiety and have a positive effect on mood.




Antibacterial research studies
Antibacterial efficacy of Withania somnifera an indigenous medicinal plant against experimental murine salmonellosis.
Phytomedicine. 2005 Mar.
We evaluated the antibacterial activity of ashwagandha root and leaves, against pathogenic bacteria. Both aqueous as well as alcoholic extracts of the ashwagandha plant (root as well as leaves) were found to possess strong antibacterial activity against a range of bacteria including Salmonella typhimurium. Moreover, in contrast to the synthetic antibiotic (viz. chloramphenicol), ashwagandha extracts did not induce lysis on incubation with human erythrocytes, advocating their safety to the living cells. Finally, the antibacterial efficacy of the ashwagandha extracts isolated from plant (both root and leaves) was determined against experimental salmonellosis in Balb/C mice. Oral administration of the aqueous extracts successfully obliterated salmonella infection as revealed by increased survival rate as well as less bacterial load in various vital organs of the treated animals.


Blood sugar
One small study found ashwagandha root was able to reduce blood sugar and cholesterol levels, and had a diuretic effect.


Brain health
Ashwagandha is used in India to treat mental deficits in geriatric patients, including amnesia. Researchers from the University of Leipzig in Germany wanted to find out which neurotransmitters were influenced by the herb. After injecting some of the chemicals in ashwagandha into rats, they later examined slices of their brain and found an increase in acetylcholine receptor activity. The researchers say, "The drug-induced increase in acetylcholine receptor capacity might partly explain the cognition-enhancing and memory-improving effects observed in animals and humans."
   A study done in 1991 at the Department of Pharmacology, University of Texas Health Science Center indicated that extracts of ashwagandha had GABA-like activity. This may account for this herb’s anti-anxiety effects.
   A 2002 laboratory study indicates ashwagandha extract stimulates the growth of axons and dendrites. A 2001 study in rodents showed the extract had memory boosting ability. A 2000 study with rodents showed it to have anti-anxiety and anti-depression effects.


Cancer
Withaferin A is a potent inhibitor of angiogenesis (new blood vessel growth). Angiogenesis 2004.
Growth inhibition of human tumor cell lines by withanolides from ashwagandha leaves.
Life Sci. 2003 Nov 21.
The leaves of ashwagandha are used in the treatment of tumors and inflammation in several Asian countries. We have isolated twelve withanolides from the leaves of this species. Compounds were tested for their anti-proliferative activity lung, colon, central nervous system and breast human tumor cell lines. Withaferin A and its derivatives exhibited inhibitory concentrations. Viscosalactone B showed the 50% inhibition. Therefore, incorporation of ashwagandha in the diet may prevent or decrease the growth of tumors in human.


Diabetes and high blood sugar
Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root.
Indian J Exp Biol. 2000.
Hypoglycemic, diuretic and cholesterol lowering effects of roots of ashwagandha were assessed on human subjects. Six mild non insulin dependent subjects and six mild high cholesterol subjects were treated with the powder of roots of ashwagandha for 30 days. Decrease in blood glucose was comparable to that of an oral hypoglycemic drug. Significant increase in urine sodium, urine volume, significant decrease in serum cholesterol, triglycerides, LDL (low density lipoproteins) and VLDL (very low density lipoproteins) cholesterol were observed indicating that this plant is a potential source of hypoglycemic, diuretic and hypocholesterolemic agents.




Lymphoma
Anticarcinogenic activity of Withania somnifera Dunal against Dalton's Ascitic Lymphoma.
J Ethnopharmacol. 2004.
The effect of ethanolic extract of ashwagandha root against Dalton's Ascitic Lymphoma has been evaluated in Swiss albino mice. A significant increase in the life span and a decrease in the cancer cell number and tumour weight were noted in the tumour-induced mice after treatment. These observations are suggestive of the protective effect of ashwagandha extract in Dalton's Ascitic Lymphoma.


Nerve cell growth
Axon- or dendrite-predominant outgrowth induced by constituents from Ashwagandha.
Kuboyama T.. Neuroreport. 2002.
We previously reported that the methanol extract of Ashwagandha (roots of Dunal) induced dendrite extension in a human neuroblastoma cell line. In this study, we found thatcompounds isolated from the methanol extract enhanced neurite outgrowth in human neuroblastoma SH-SY5Y cells.


Nitric oxide production
Induction of nitric oxide synthase expression by ashwagandha in macrophages.
Iuvone T, Esposito G, Life Sci. 2003.
Ashwagandha may induce the synthesis of inducible nitric oxide synthase expression likely by acting at transcriptional level. The increased nitric oxide production by macrophages could account, at least in part, for its immune stimulating properties.


I give Lucy 1 capsule with her AM meal.