Not just Holistic, but how to use E: All of the Above!

We made this blog because we did tons of research on success stories and research worldwide and used it on my dog with nasal cancer named Lucy. Oddly, my hobby is molecular biology. The treatment uses combination of health store supplements, some prescription meds, diet changes, and specific Ayurvedic and Chinese medicinal herbs. We just wanted her to have a better quality of life. We thought this combination of E: All the Above (except no radiation or chemo) would help that for sure, but it actually put her bleeding nasal cancer in remission!
Our approach to cancer is about treating the whole animals biologic system as natural as possible. But I do hate the word 'Holistic'. Sounds like hoo hoo. This is science based, research based data and results of using active herbal compounds that happen to be readily available and common. Some call it Nutriceuticals. Others may call it Orthomolecular cancer therapy. Or Cancer Immunotherapy.
WE FEEL DIVERSITY IN TREATMENT IS KEY:
-Kill the cancer cells
-Rid the cancer cells
-Remove the toxins it produces
-Make cancer cells become easier targets for the immune system
-Slow cancer cell reproduction
-Stimulate AND modulate the immune system
-Control secondary symptoms like bleeding, infection, inflammation, mucous, appetite, or pain for a better feeling animal.
-Working with your vet for exams and prescriptions that are sometimes needed when conditions are acute.
Just by using a multi-modal treatment approach that is as diverse in attack as possible. Both conventional and natural.
The body conditions that allowed it to develop in the first place must be corrected. If caught early enough, like with Lucy, this ongoing maintenance correctional treatment is all that was required at this point to achieve, so far, more than 10 TIMES the life expectancy (48 months so far) after diagnosis WITH remission. I did not use radiation or chemotherapy.
I hope this cancer research can help your dog.
Lucy's nasal cancer is still in remission!

Lucy

Lucy

April 22, 2015

LUCY has made it to her 4 FOUR YEAR anniversary




Well, she made to her 4 FOUR YEAR anniversary of her diagnosis by biopsy of nasal cancer!

She got Tri Tip Steak! And mashed potatoes and green beans! And whipped cream for dessert! All without any pills in it! Well, for that day anyway.


She really has not progressed. No bumps. Some mucous sometimes. Sometimes a little eye tearing on that side. Hardly ever any bleed and very little if one. Four years ago she was bad.






She was so happy she wouldn't keep still!



Lucy never did radiation or chemo, she only did the Tippner Protocol. The Tippner Cancer Protocol combines immunotherapy and molecular cancer therapy using off the shelf readily available inexpensive natural substances. Here is her list. She is past 4 years after diagnosis by biopsy

I buy most of the stuff from Swanson Vitamins. They are cheaper, in capsules for dosage changes, and carry almost everything I give to Lucy except for the Chinese Herbs Stasis Breaker prescription, and the Low Dose Naltrexone prescription. Here is a $5 off coupon link I found


Cancer and inflammation : Curcumin COX and PG-2 Pan-erb





Cell Membrane Receptors and Cancer
In recent years cancer researchers have discovered that an important part of the puzzle in cancer development lies in the expression of certain cell membrane receptors and their stimulation by various chemical agents (ligands). Stimulation of various cell membrane receptors by specific ligands produce profound effects on cellular proliferation, cell growth, cell differentiation and apoptosis (programmed cell death). As an example, the binding of vitamin D to the vitamin D receptor on the cell membrane, triggers a series of reactions (known as signal transduction) that ultimately promotes the induction of intracellular messengers, which slow the rate of cell division, and promotes cell maturation; two outcomes linked to reduction of cancer development.

On the other hand the over-expression of Epidermal Growth Factor Receptors (EGFR) and other members of the tyrosine kinase family are frequently indicated in epithelial cancers, including colon cancer.

The epidermal growth factor (EGF) family of receptor tyrosine kinases consists of four receptors, EGF-R (ErbB1), ErbB2 (Neu), ErbB3, and ErbB4.

In response to these discoveries, pharmaceutical companies have produced a number of drugs that inhibit the activation of specific receptors of the EGFR series (EGFR inhibitor drugs). However, in general these drugs have had limited success because cancer cells usually possess more than one type of EGFR receptor. As such, researchers conclude that what is needed to help prevent colon cancer, as well to help treat colon cancer, is a broad-spectrum EGFR receptor inhibitor that inhibits signal transduction for all EGFR cell membrane receptors. (pan-erb signal transduction inhibitors).
To this end there is a naturally-occurring pan-erb signal transduction inhibitor that is showing promise in experimental and animal studies, known as EGFR Related Protein. This protein occurs naturally and thus, its use as a targeted therapeutic agent is unlikely to produce toxic side effects.

Curcumin Is A Natural Pan-erb Signal Transduction Inhibitor In Cancer Prevention

With respect to natural medicine, it is well documented that curcumin, the active ingredient in the spice turmeric, also acts as a powerful inhibitor of EGFR receptors. Experimental studies, animal studies and a recent Phase I clinical trial, have shown that curcumin inhibits the growth of colon cancer cells and reduces tumor incidence in high risk human subjects. Curcumin inhibits the EGFR receptor, which in turn inhibits the propagation of metabolic reactions (e.g. decreased synthesis of the tumor promoting messenger NF-kB) leading to inhibition of cell replication of cancer cells and preneoplastic cells.

Curcumin also exerts anti-inflammatory effects on cells by inhibiting synthesis of pro-inflammatory prostaglandins. Inhibiting pro-inflammatory prostaglandins has also been shown to reduce risk of colon cancer as demonstrated by studies linking the effects of aspirin and other non-steroidal anti-inflammatory drugs to reduced incidence of colon cancer. However, unlike aspirin, curcumin does not cause gastrointestinal erosion leading to ulceration and bleeding disorders.


Prostaglandin series-2 and its metabolites have been shown to contribute to the cancer processes through one or more of several mechanisms including increased proliferation, apoptosis, enhanced carcinogen metabolism or modulation of the immune system


Also:
Gummy exudates of the herb boswellia have been traditionally used as anti-arthritic and anti-cancer medications. Boswellic acid and its acetates isolated from these gummy exudates were found to be inhibitors of topoisomerases and to be non-redox, non-competitive specific inhibitors of 5-lipoxygenase (5-LOX). All of these properties are key factors in preventing and controlling cancer. Experimental evidence has shown that boswellic acid acetates isolated from Boswellia carterri Birdw inhibit cell growth and induce apoptosis (programmed cell death) in prostate cancer cells by inhibition of 5-lipoxygenase. Other studies have shown that boswellic constituents exhibited potent cytotoxic activities against three types of human neuroblastoma cells.



Summary
A strong body of evidence indicates that an important aspect of cancer prevention involves containment of prostaglandin series-2 synthesis and inhibition of cell membrane receptors associated with the receptor tyrosine kinase family (EGFR, ErB-2, ErB-3 and ErB-4). Curcumin, derived from the spice turmeric, has shown significant anti-tumor properties against colon cancer. Curcumin has been shown to inhibit the receptor tyrosine kinase family and decreases synthesis of prostaglandin series-2. The anti-inflammatory herbs ginger, boswellia and white willow bark extract have also been shown to inhibit prostaglandin series-2 synthesis, as well as other pro-inflammatory mediators, and experimental evidence suggests that their active constituents possess important anti-tumor properties. As such, health practitioners may wish to encourage their patients to ingest a herbal combination supplement product each day containing curcumin, ginger, white willow bark extract and boswellia, as an additional part of a wellness and cancer prevention program. This may have important applications especially in regards to colon cancer, the second leading cause of cancer death.


Link to Original Text Article 


References:

Reddy S, Rishi A.K., Xu H et al. Mechanisms of curcumin-and EGF-receptor related protein (ERRP) – dependent growth inhibition on colon cancer cells. Am J Clin Nutr, 55; 2: 185-194. 2006

Ciardiello, F, Caputo R,  Bianco, R.  Antitumor Effect and Potentiation of Cytotoxic Drugs Activity in Human Cancer Cells by ZD-1839 (Iressa), an Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor.  Clinical Cancer Research; 6: 2053-2063, May 2000

Ciardiello F and Tortora G. Interactions between the epidermal growth factor receptor and type I protein kinase A: biological significance and therapeutic implications. Clinical Cancer Research, 4,; 4: 821-828: 1998

Al-Achi. Anti-inflammatory Herbs. U.S. Pharmacist. 29:03 (Posted 03/15/2004)

McCarty M.F. Targeting Multiple Signaling Pathways as a Strategy for Managing Prostate Cancer: Multifocal Signal Modulation Therapy. Integrative Cancer Therapies 3; 4:349-380. 2004

Wells, A. EGF receptor. Int. J. Biochem. Cell Biol., 31: 637-643. 1999.



Lucy takes 1 capsule of  COX-2 Combo from swansonvitamins.



Lucy never did radiation or chemo, she only did the Tippner Protocol. The Tippner Cancer Protocol combines immunotherapy and molecular cancer therapy using off the shelf readily available inexpensive natural substances. Here is her list. She is past 3 years after diagnosis by biopsy

I buy most of the stuff from Swanson Vitamins. They are cheaper, in capsules for dosage changes, and carry almost everything I give to Lucy except for the Chinese Herbs Stasis Breaker prescription, and the Low Dose Naltrexone prescription. Here is a $5 off coupon link I found


March 25, 2015

Can it help Osteosarcoma?



"Gary, my dog  got osteosarcoma in mid November. I have used your protocol for Lucy with some variations. Without you, he would be dead. Instead, he still has a  tumour on his leg but it's smaller and he is happy and mobile. He needs no pain meds. I thank you from the bottom of my heart. The photo is him a couple of days ago. His vet can't believe how well he is doing. He was given just a few weeks to live. We live in Ontario, Canada. Here is a link to our blog on his condition
http://www.greatdaneangels.org/dog-blog/2015/3/24/bone-cancer-remission-in-dogs"









Lucy never did radiation or chemo, she only did the Tippner Protocol. The Tippner Cancer Protocol combines immunotherapy and molecular cancer therapy using off the shelf readily available inexpensive natural substances. Here is her list. She is past 3 years after diagnosis by biopsy

I buy most of the stuff from Swanson Vitamins. They are cheaper, in capsules for dosage changes, and carry almost everything I give to Lucy except for the Chinese Herbs Stasis Breaker prescription, and the Low Dose Naltrexone prescription. Here is a $5 off coupon link I found


February 17, 2015

Lucy Nasal Cancer Status Report




Sorry, I have been busy and have not posted status. I should have posted during the holidays as you will read below.

Lucy is doing very well. Her left nostril (her side with nasal cancer) breathing opened up to what appears to be 100% again a few weeks after Christmas. She appears to have equal breathing out of both sides and no mucous problems.
HOWEVER for 3 weeks around the holidays she had quite a few bleeds (some bad like she used to have when first diagnosed) then a mild infection and then metallic (iron) smelling mixed discharge. Occasionally yellow. But I stepped up giving the Yunnan Bai Yao again (2x to 3x dosage 3x a day) and colloidal silver during those few weeks (man that was stressful) and it calmed down. Once the bleeding stopped and the infection cleared her breathing became normalized all of a sudden.
Now, her left side has had, since about the last 8-10 months, no mucous and no problem discharge and no bleeds to speak of, the breathing output on that side was diminished to a guesstimate about half of normal or less. I gave Meloxicam to lessen for periods during the last 8 months for what I would guess was swelling but it did nothing. Except upset her stomach.  I don't understand what happened here with the problems during the holidays, but she is now fine again and in what appears to be 100% remission again for the last month at least. She was in 100% remission about 4 months in to protocol usage in 2011. And the 100% lasted about 3 years. This last year she simply had diminished breathing ability on that left side, so I could not say 100% during that time. But now she is back to great for now. Dunno. Pretty wild.






Lucy never did radiation or chemo, she only did the Tippner Protocol. The Tippner Cancer Protocol combines immunotherapy and molecular cancer therapy using off the shelf readily available inexpensive natural substances. Here is her list. She is past 3 years after diagnosis by biopsy

I buy most of the stuff from Swanson Vitamins. They are cheaper, in capsules for dosage changes, and carry almost everything I give to Lucy except for the Chinese Herbs Stasis Breaker prescription, and the Low Dose Naltrexone prescription. Here is a $5 off coupon link I found


December 18, 2014

Supporting the Immune system is critical


Supporting the Immune system is beneficial, and (quoted)
"a diet supplemented with fish oil and the amino acid arginine appears to increase survival time in dogs with lymphoma, a cancer that affects white blood cells.
Dogs with this kind of cancer, similar to non-Hodgkin's lymphoma in humans, are easily treated, but as with humans, their cancer tends to return. A team of researchers led by Dr. Gregory Ogilvie of Colorado State University in Fort Kent, studied the effects of adding fish oil and arginine to the diets of 32 dogs being treated for lymphoma.
Half of the dogs received a special chow with the two supplements in it, and the other half ate chow with soybean oil added. The two chows were identical in nutritional value, and formulated to be equally tasty to the dogs. All the dogs were being treated with the anti-cancer drug doxorubicin every three weeks, and were living at home with their owners.
Previous research has shown that some polyunsaturated fatty acids, like those found in fish oil, may help prevent the growth and spread of cancer tumors, and may help prevent cachexia -- the devastating weight loss and muscle wasting seen in some cancer patients despite adequate nutrition. Likewise, arginine supplements have been reported to improve immune responses, and might help the body fight cancer.
The dogs were fed one of the chows twice a day during and after their cancer treatment. The researchers report that compared to the control dogs, those who ate the supplemented chow showed higher blood levels of two fatty acids called C20:5 and C22:6 that seem particularly effective in fighting cancer. Dogs with more of these fatty acids in their blood also tended to have more normal levels of lactic acid, which tends to accumulate in the blood when metabolism is disrupted in cancer patients.
In addition, report Ogilvie and colleagues, the dogs with higher levels of these two fatty acids survived longer than those with lower levels, and had longer remissions, periods of time before their disease came back.
Writing in the journal Cancer, the researchers suggest that the fatty acids may help both dogs and humans by slowing down the spread of cancer cells and by increasing the cells' susceptibility to anti-cancer drugs like the doxorubicin used in this study.
Ogilvie and colleagues also note their findings fit in with previous research showing that the fatty acids they studied appear to help fight cancer and its effects in both humans and animals."
SOURCES:
Reuters Health, April 28, 2000
The journal Cancer, May 2000; 88:1916-1928



Lucy never did radiation or chemo, she only did the Tippner Protocol. The Tippner Cancer Protocol combines immunotherapy and molecular cancer therapy using off the shelf readily available inexpensive natural substances. Here is her list. She is past 3 years after diagnosis by biopsy

I buy most of the stuff from Swanson Vitamins. They are cheaper, in capsules for dosage changes, and carry almost everything I give to Lucy except for the Chinese Herbs Stasis Breaker prescription, and the Low Dose Naltrexone prescription. Here is a $5 off coupon link I found