Not just Holistic, but how to use E: All of the Above!

I made this blog because I did tons of research on success stories and research worldwide and used it on my dog with nasal cancer named Lucy. So, now my hobby is molecular biology. The treatment uses combination of health store supplements, some prescription meds, diet changes, and specific Ayurvedic and Chinese medicinal herbs. I just wanted her to have a better quality of life. I thought this combination of E: All the Above (except no radiation or chemo and surgery for this cancer was not an option) would help that for sure, but it actually put her bleeding nasal cancer in remission!
My approach to cancer is about treating the whole animals biologic system. But I do hate the word 'Holistic'. Sounds like hoo hoo. This is science based, research based data and results of using active herbal compounds that happen to be readily available and common. Some call it Nutriceuticals. Others may call it Orthomolecular cancer therapy. Or Cancer Immunotherapy.
-Slow cancer cell reproduction
-Make cancer cells become easier targets for the immune system
-Kill the cancer cells
-Rid the cancer cells
-Remove the toxins it produces
- Stimulate and Modulate the immune system
-Control secondary symptoms like bleeding, infection, inflammation, mucous, appetite, or pain for a better feeling animal
-Working with your vet for exams and prescriptions that are sometimes needed when conditions are acute.
Just by using a multi-modal treatment approach that is as diverse in attack as possible. Both conventional and natural.
The body conditions that allowed it to develop in the first place must be corrected. If caught early enough, like with Lucy, this ongoing maintenance correctional treatment is all that was required at this point to achieve, so far, more than 10 TIMES the life expectancy given (more than 60 months) after diagnosis WITH remission. I did not use radiation or chemotherapy or surgery.
I hope this cancer research can help your dog as well.

My Lucy

My Lucy
In Loving Memory my Lucy December 2016
CURRENT STATUS - It was for more than 5 YEARS after Lucy was diagnosed by biopsy in March 2011 with nasal cancer that she lived. And she was in remission for 4 of 5 years using no radiation or chemo! Now multiply that by 7 to be 35 years extended!! She was 12.5 years old - equivalent to almost 90 human years old. She ended her watch December 1, 2016. I miss her so much.

February 24, 2012

Common Supplement Dosage Amounts for Dogs

Can I give.... What dosage should I use?

Common Supplement Dosage Amounts for Dogs as per Vet *googled average:

Small Dogs
  • Vitamin A: 1,000 mg twice a day
  • Vitamin C: 500 mg twice a day
  • Bioflavonoid & Quercitin: 1/4 human dose
  • Vitamin E: 50 IUs twice a day
  • Vitamin B complex: 1/4 human dose
  • Selenium: 10 mcg
  • Bromelain: 50 mg twice a day
  • Digestive enzymes with pancreatin: 1/4 human dose
  • Glutamine: 1/4 human dose
  • L- Arginine: 1/4 human dose - this is a big part of Hills Dog Cancer Canned Food
  • Flaxseed Oil: 1 tsp. twice a day
  • Garlic: 1/4 chopped Clove
Medium Dogs
  • Vitamin A: 2,500 mg twice a day
  • Vitamin C: 1,000 mg twice a day
  •  Bioflavonoid & Quercitin: 1/2 human dose
  • Vitamin E: 200 IUs twice a day
  • Vitamin B complex: 1/2 human dose
  • Selenium: 25mcg
  • Bromelain: 100 mg twice a day
  • Digestive enzymes with pancreatin: 1/2 human dose
  • Glutamine: 1/2 human dose
  • Arginine: 1/2 human dose
  • Flaxseed Oil: 1/2 tbs. twice a day
  • Garlic: 1/2 chopped Clove
Large Dogs
  • Vitamin A: 5,000 mg twice a day
  • Vitamin C: 2,000 mg twice a day
  • Bioflavonoid & Quercitin: Human dose
  • Vitamin E: 400 IUs twice a day
  • Vitamin B complex: Human dose
  • Selenium: 50mcg
  •  Bromelain: 200 mg twice a day
  • Digestive enzymes with pancreatin: Human dose
  • Glutamine: Human dose
  • Arginine: Human dose
  • Flaxseed Oil: One tablespoon a day
  • Garlic: One chopped Cloves

February 21, 2012

What kinds of cancer occur in dogs?

What kinds of cancer occur in dogs?

In dogs generally 50 per cent of all tumors are of the skin (of which about 40 per cent are malignant and 60 per cent benign), 20 per cent are of the mammary glands (which account for 58 per cent of tumors in bitches, of which about 50 per cent are benign), only 10 per cent are of the alimentary system (which is one of the prime sites in Man), 10 per cent of the lymphatic system, 5 per cent of the reproductive system, and 5 per cent others.

However, bone tumors are much more common in the large and giant breeds. They are most likely to occur at the ends of long bones in the growth plates but may occur on the skull, pelvis, etc. Bone tumors are mostly extremely malignant. Signs are swelling, pain, heat, and lameness (if the tumor is in a limb bone). However, although bone tumors on the forelimb (especially at the distal [lower] end of the radius/ulna - just above the knee joint and a favorite site) or those on the distal end of the tibia/fibula (just above the hock joint) on the hind leg are easy enough to detect, particularly when the typical hard swelling starts, those in other sites can be much more difficult to diagnose. This is especially so if they are on bones where there is heavy surrounding musculature, such as the shoulder-blade, upper arm, or thigh. These are all too likely to be diagnosed as pulled muscles, damaged tendons, arthritis, etc. Also, osteosarcoma (the most common form of bone cancer in these breeds) often starts up after some kind of trauma such as a collision or fall and is most likely to occur in the age range of 6 to 8 years, so the tendency is for a diagnosis of bruising, arthritis, etc. in any case.

Oral tumors are quite common and mostly malignant. One problem is that they are often well advanced before being noticed. Signs are bloody saliva, bad breath, difficulty in eating, or unwillingness to eat. Malignant melanoma are particularly dangerous and spread rapidly.

Nasal tumors are quite rare but mostly malignant. Signs are sneezing, difficulty in breathing, discharge from the 
nose, or nosebleeds. They do not spread quickly but cause much local damage.

Tumors of the gut are rare but usually malignant and generally well advanced by the time they are noticed. Spleen tumors are usually malignant with early secondaries. Signs of internal tumors are non-specific but include weight loss (sometimes rapid), diarrhea or constipation, pain which may be shown by a stiffness of movement, passage of blood or vomiting of blood or "coffee-grounds", and loss of appetite.

Tumors of the lungs (a prime site in Man) do not occur as primaries in dogs but frequently as secondaries. Signs are difficulty in breathing, particularly after exercise, coughing, and wheezing.

Cancer of the lymph system is quite common and can involve a combination of lymph glands, bone marrow, circulating blood, and internal organs. Signs are enlargement of glands, depression, anorexia, and weight loss. These cancers include lymphosarcoma and leukemia. There are two types of canine lymphoma: the multicentric which affects the whole body, and one which develops only in the alimentary, cutaneous, and thymic glands.

Skin tumors can vary from granuloma, which are pea-sized, to vast lumps. Not all lumps which appear on the skin are tumors. Sebaceous cysts are very common, particularly in the elderly dog, but are only blocked sebaceous glands and quite harmless, although they do sometimes burst. It is a good rule, though, to have any lump tested.

February 17, 2012

Cottage Cheese and Flax Oil for Cancer?

Though there are many sources, we only have anecdotal data re pets (which is in fact similar to the situation we have with humans). The evidence we do have however does point to there being a good chance that feeding flax oil and cottage cheese blended together may/will yield health benefits for sick as well as healthy pets. Interestingly, animal experiments* have shown similar beneficial results when feeding flaxseed to animals with artificially induced cancer

In Das Fettsyndrom and other books she wrote, Dr. Budwig quotes a farmer who told her: ”We give flaxseed to all our livestock. Why? Well, cattle that gets flaxseed oil simply never falls ill. Our cattle are never sick, even when there is tooth and claw disease in the village.” 

Thrombocytopenia in dog dramatically improved
(from a Budwig protocol support group)
A c. 30 lbs dog with thrombocytopenia used to have terrible bleeding episodes every 2 weeks, requiring prednisone to get her through each crisis. A week or two after additionally introducing flax oil/cottage cheese mix to the dog’s homemade cancer diet, the bleeding episodes stopped and hadn’t recurred by the time of reporting (7 weeks later). Additionally, the dog’s energy had remarkably increased. Nothing else in the dog’s diet or lifestyle was changed. While initially receiving 2 tbs of flax oil daily for 1 month, the dog is now given the mix only every other day.

Lucy simply acted peppier within a week of this. Dunno. Seemed to help her.
Read more

February 14, 2012

Chinese Herbal Medicine for Dog Cancer

Chinese Herbal Medicine

Chinese Herbal Medicine is another branch of Traditional Chinese Medicine (TCM). In fact, approximately 80% of all traditional Chinese medical patients are treated with herbs, while only the remaining 20% are treated with acupuncture or other manual therapies. Chinese Herbal Medicine has ancient roots in China. An archaeological dig in 1973 near Changsha, China revealed silk scrolls dating back to 168BC containing 170 different medicinal prescriptions to treat over 52 diseases. An ancient text dated 220AD, Jin Gui Yao Lue (Prescriptions of the Golden Cabinet) contains the formulation of a Chinese herbal prescription called Rehmannia 8 that is still commonly used in the West today.


Herbal medicines are typically quite inexpensive when compared to pharmaceutical drugs, although if tonic formulas are employed for a long period of time the price can add up. For a 50 pound dog, a typical tonic herbal formula will cost approximately $20/month. However, this is a small price to pay for the relief of symptoms and the strengthening of the body! Chinese herbal formulas come in a variety of forms including raw herbs, powdered herbs, liquids, capsules, and teapills. Teapills, small pea sized pills with a tough outer coating, are most often used for small animals, along with capsules and liquids, due to their ease of administration. Powders can also be mixed into foods, but cats are usually too suspicious to fall for that! Fortunately, most formulas come in a variety of forms so many options exist to accommodate both owner and pet.
Although herbal medicines are not without any side effects, in general the side effects are mild and quickly resolve when the herb is withdrawn.  It is recommended to owners that the herbal formula be started slowly to monitor for any type of reaction. Typically a reaction just means the wrong herbal formula was chosen or the animal has an intolerance to a specific ingredient in the formula. Occasionally, a reaction will be seen after the animal has been on the formula for many months. This typically indicates that the formula is no longer needed and that the body is able to keep itself in balance without the herbs. Herbal formulas not sold under the Good Manufacturing Practices on label (GMP) should not be used, as these commonly are contaminated with heavy metals, pesticides, or pharmaceutical drugs. Occasionally, they will even contain endangered species. Most herbal formulas sold to herbal practitioners follow the GMP. However, products found in local Chinatown pharmacies are of questionable purity.

An example of Chinese Herbal Medicine for Dog Cancers are Stasis Breaker (a tumor buster) and Wei Qi Booster (immune booster) that I use.

Stasis Breaker Tumor Buster
Bai Hua She She Cao - Oldenlandia
Ban Zhi Lian - Scutellaria
E Zhu-Zedoaria
Mu Li(Shu)-Ostrea
San Leng-Sparganium
Zhe Bei Mu - Fritillaria

Classical Antecedent:

Nei Xiao Wan from Wei Sheng Bao Jian (Precious Mirror of Health) written by Luo Tian Yi in Yuan dynasty (1279-1368).
What is in Nei Xiao Wan
What is the Nei Xiao Wan formula composition?
A proprietary blend of
Bulbus Fritillariae Thunbergii
Radix Et Rhizoma Rhei
Radix Platycodi Grandiflori
Spica Prunellae Vulgaris
Radix Scrophulariae Ningpoensis
Radix Glycyrrhizae Uralensis
Radix Ampelopsis Japonicae
Radix Angelicae Sinensis
Fructus Aurantii
Fructus Forsythiae Suspensae
Radix Rehmanniae Glutinosae
Herba Menthae Haplocalycis
Natrii Sulfas
Radix Trichosanthis Kirilowii
Concha Meretricis Seu Cyclinae
(Bei Mu)
(Shu Da Huang)
(Jie Geng)
(Xia Ku Cao)
(Xuan Shen)
(Gan Cao)
(Bai Lian)
(Dang Gui)
(Zhi Qiao)
(Hai Zao)
(Lian Qiao)
(Di Huang)
(Bo He)
(Mang Xiao)
(Tian Hua Fen)
(Qing Yan)
(Hai Ha Fen)

Wei Qi Booster Immune Booster
Oldenlandia - Bai Hua She She Cao

Scutellaria - Ban Zhi Lian
Citrus - Chen Pi
Angelica - Dang Gui
Codonopsis - Dang Shen
Astragalus - Huang Qi
Lindera - Wu Yao
Scrophularia - Xuan Shen.

Classical Antecedent:
Si Jun Zi Tang from Tai Ping Hui Min He Ji Ju Fang (Imperial Grace Formulary of the Tai Ping Era) written by Chen Shi Wen et al in 1080.
What is the Si Jun Zi Tang formula composition?
A proprietary blend* of
Radix Codonopsis Pilosulae
Rhizoma Atractylodis Macrocephalae
Sclerotium Poriae Cocos
Radix Glycyrrhizae Preparata
(Dang Shen)
(Bai Zhu)
(Fu Ling)
(Zhi Gan Cao)

Laboratory studies are expanding the clinical knowledge that is already documented in traditional texts. The herbs that are traditionally used for anti-cancer treatment and that are anti-angiogenic through multiple interdependent processes (including effects on gene expression, signal processing, and enzyme activities) include:

Artemisia annua (Chinese wormwood) (Artemisinin)

Viscum album (European mistletoe)
Curcuma longa (curcumin)
Scutellaria baicalensis (Chinese skullcap)
Resveratrol and proanthocyanidin (grape seed extract)
Magnolia officinalis (Chinese magnolia tree)
Camellia sinensis (green tea)
Ginkgo biloba
Poria cocos
Zingiber officinalis (ginger)
Panax (Red) ginseng
Rabdosia rubescens hora (Rabdosia)
Chinese destagnation herbs.

Natural health products target molecular pathways other than angiogenesis, including epidermal growth factor receptor, the HER2/neu gene, the cyclo-oxygenase-2 enzyme, the nuclear factor kappa-B transcription factor, the protein kinases, the Bcl-2 protein, and coagulation pathways. 

A number of Chinese botanicals display anti-cancer activity and
may be beneficial for a broad array of cancer patients, no matter what their TCM pattern indicates.37 38 Herbs such as astragalus and angelica activate the immune system and display antitumor activity. 39 Others, like Oldenlandia
diffusa, encourage apoptosis. 40 A meta-analysis evaluated the evidence from randomized trials concerning the combination of astragalus-containing Chinese herbal products with platinum-based chemotherapy. The literature analysis revealed improved survival, tumor response, and diminished toxicity as a result of the combination.41

My dog Lucy has been on these for many months for her nasal cancer and went into remission after 4 months on them (plus diet changes, other supplements and Low Dose Naltrexone) and still is today. The entire program I created for her uses diet, supplements, a minor prescription, and the above herbs. Kitchen sink, yes, but it is working.
Have your vet order that stuff (ONLY A VET CAN ORDER....) from (I am not affiliated with this herb company but it's the only herb compounds that I can find people having success with. So I am using it in addition to all the other herbs. And Lucy is still great)
Go ahead and Google Stasis Breaker.

1 Xie H. How to select Chinese herbal medicine for cancer patients. American Journal of Traditional Chinese Veterinary Medicine. 2006;1(1):49-52.
2 Xu W, Towers AD, Li P, et al. Traditional Chinese medicine in cancer care: perspectives and experiences of patients and professionals in China. European Journal of Cancer Care. 2006;15:397-403.
3 Wong R, Sagar CM, and Sagar SM. Integration of Chinese medicine into supportive cancer care: a modern role for an ancient tradition. Cancer Treatment Reviews. 2001;27:235-246.
4 Reisfield GM and Wilson GR. Use of metaphor in the discourse on cancer. Journal of Clinical Oncology. 2004;22(19):4024-4027.
5 Penson RT, Schapira L, Daniels KJ, et al. Cancer as metaphor. The Oncologist. 2004;9:708-716.
6 Xu W, Towers AD, Li P, et al. Traditional Chinese medicine in cancer care: perspectives and experiences of patients and professionals in China. European Journal of Cancer Care. 2006;15:397-403.
7 World Health Organization (online 202) WHO Traditional Medicine Strategy 2002-2005. Obtained at on 03-15-07.
8 White House Commission on Complementary and Alternative Medicine Policy, 2002. Obtained at on 03-15-07.
9 Cragg GM, Boyd MR, Cardellina JH, et al. Ethnobotany and drug discovery: the experience of the US National Cancer Institute. 1994 Ethnobotany and the search for new drugs. Wiley, Chichester (Ciba Foundation Symposium 185), pp. 178-196.
10 Kaphle K, Wu L-S, Yang N-YJ, et al. Herbal medicine research in Taiwan. eCAM. 2006;3(1):149-155.
11 Xie H. How to select Chinese herbal medicine for cancer patients. American Journal of Traditional
Chinese Veterinary Medicine. 2006;1(1):49-52.
12 Kaphle K, Wu L-S, Yang N-Y J, and Lin J-H. Herbal medicine research in Taiwan. eCAM. 2006;3(1):149-155.
13 Lana SE, Kogan LR, Crump KA, Graham JT, and Robinson NG. The use of complementary and alternative therapies in dogs and cats with cancer. J Am Anim Hosp Assoc. 2006;42:361-365.
©2007 Narda G. Robinson, DO, DVM, MS. All rights reserved.
14 American Cancer Society. Guide to Complementary and Alternative Cancer Methods. 2000. P. 196.
15 Xie H. How to select Chinese herbal medicine for cancer patients. American Journal of Traditional Chinese Veterinary Medicine. 2006;1(1):49-52.
16 Wong R, Sagar CM, and Sagar SM. Integration of Chinese medicine into supportive cancer care: a modern role for an ancient tradition. Cancer Treatment Reviews. 2001;27:235-246.
17 Wong R, Sagar CM, and Sagar SM. Integration of Chinese medicine into supportive cancer care: a modern role for an ancient tradition. Cancer Treatment Reviews. 2001;27:235-246.
18 Xiu HM and Liu JX. Advances in TCM treatment for metastasis of tumors. Journal of Traditional Chinese Medicine. 2003;23(2):151-157.
19 Wong R, Sagar CM, and Sagar SM. Integration of Chinese medicine into supportive cancer care: a modern role for an ancient tradition. Cancer Treatment Reviews. 2001;27:235-246.
20 Wong R, Sagar CM, and Sagar SM. Integration of Chinese medicine into supportive cancer care: a modern role for an ancient tradition. Cancer Treatment Reviews. 2001;27:235-246.
21 Wong R, Sagar CM, and Sagar SM. Integration of Chinese medicine into supportive cancer care: a modern role for an ancient tradition. Cancer Treatment Reviews. 2001;27:235-246.
22 Sang H and Wu B. Clinical and experimental research into treatment of hysteromyoma with promoting qi flow and blood circulation, softening and resolving hard lump. Journal of Traditional Chinese
Medicine. 2004;24(4):274-279.
23 Marsden S, Messonnier S, and Yuill C. Traditional Chinese Medicine. Obtained at on 02-17-07.
24 Jiang W-Y. Therapeutic wisdom in traditional Chinese medicine: a perspective from modern science.
TRENDS in Pharmacological Sciences. 2005;26(11):558-563.
25 Cohen I, Tagliaferri M, and Tripathy D. Traditional Chinese Medicine in the treatment of breast cancer.
Seminars in Oncology. 2002;29(6):563-574.
26 Takeichi M and Sato T. Studies on the psychosomatic functioning of ill-health according to Eastern and
Western Medicine 1. Visual observation of the sublingual vein for early detection of vital energy stagnation and blood stasis. American Journal of Chinese Medicine. 1999;27(1):43-51.
27 Wang JF, Cai CZ, Kong CY, et al. A computer method for validating Traditional Chinese Medicine herbal prescriptions. American Journal of Chinese Medicine. 2005;33(2):281-297.
28 Wang JF, Cai CZ, Kong CY, et al. A computer method for validating Traditional Chinese Medicine
herbal prescriptions. American Journal of Chinese Medicine. 2005;33(2):281-297.
29 Xie H. How to select Chinese herbal medicine for cancer patients. American Journal of Traditional Chinese Veterinary Medicine. 2006;1(1):49-52.
30 Wang S, Zheng Z, Weng Y, et al. Angiogenesis and anti-angiogenesis activity of Chinese medicinal
herbal extracts. Life Sciences. 2004;74:2467-2478.
31 Zhang T, Ma S-L, Xie G-R, et al. Clinical research on nourishing Yin and unblocking meridians recipe combined with opioid analgesics in cancer pain management. Chin J Integr Med. 2006;12(3):180-184.
32 Deng W-P, Chao M-W, Lai W-F, et al. Correction of malignant behavior of tumor cells by traditional Chinese herb medicine through a restoration of p53. Cancer Letters. 2006;233:315-327.
33 Wong WCW, Lee A, Wong SYS, et al. Strengths, weaknesses, and development of Traditional Chinese Medicine in the health system of Hong Kong: through the eyes of future Western doctors. Journal of Alternative and Complementary Medicine. 2006;12(2):185-189.
34 Coyle M and Smith C. A survey comparing TCM diagnosis, health status and medical diagnosis in women undergoing assisted reproduction. Acupuncture in Medicine. 2005;23(2):62-69.
35 Zhang GG, Lee W, Bausell B, et al. Variability in the Traditional Chinese Medicine TCM) diagnoses and herbal prescriptions provided by three TCM practitioners for 40 patients with rheumatoid arthritis.
Journal of Alternative and Complementary Medicine. 2005;11(3):415-421.
36 Zhang GG, Bausell B, Lao L, et al. The variability of TCM pattern diagnosis and herbal prescription on rheumatoid arthritis patients. Alternative Therapies. 2004;10(1):58-63.
37 Wynn SG and Fougere BJ. Veterinary Herbal Medicine. St. Louis: Mosby, Inc. 2007. P. 308.
38 Xie H. How to select Chinese herbal medicine for cancer patients. American Journal of Traditional Chinese Veterinary Medicine. 2006;1(1):49-52.
39 Wong R, Sagar CM, and Sagar SM. Integration of Chinese medicine into supportive cancer care: a modern role for an ancient tradition. Cancer Treatment Reviews. 2001;27:235-246. 
40 Yadav, SK and Lee SC. Evidence for Oldenlandia diffusa-evoked cancer cell apoptosis through superoxide burst and capsase activation. Journal of Chinese Integrative Meidcine. 2006;4(5):485-489.
41 McCulloch M, See C, Shu X-J, et al. Astragalus-based Chinese herbs and platinum-based chemotherapy
for advanced non-small-cell lung cancer: meta-analysis of randomized trials. Journal of Clinical Oncology. 2006;24(3):419-430.
42 Meijerman I, Beijnen JH, and Schellens JHM. Herb-drug interactions in oncology: focus on mechanisms of induction. Oncologist. 2006;11:724-752.

February 11, 2012



The following home-made cancer diet I used , and follows the "low carbs, high fat, moderate protein" principle. It is important to understand that some additional supplementation (eg. high-quality daily dog multi vitamin) is needed for complete nutrition.

Hi, I did give fresh cooked food, half home cooked, other half kibble.
The fresh cooked (well I would cook enough for about 5-6 days) was frozen ground chub of turkey that I would pan fry in coconut oil. I would add blueberries, canned carrot, canned spinach to this cooking, and then add half dozen eggs and cook it all. Never raw.
  • At serving time I add high quality GRAIN FREE kibble,  half kibble half homemade dog cancer diet recipe. The kibble adds texture to hide pills mouth feel. Served with a little warm water to make gravy and aroma. I would simply drop the pills in and fork mix and serve.

  • You can add sweet potato or canned pumpkin(not can pumpkin pie filling) as well. The pumpkin is great for sick tummies. And it is very good for them.

February 8, 2012

NSAIDS for Cancer Therapy

Piroxicam, an NSAID, is a non-selective Cox-1 and Cox-2 inhibitor and has anti-cancer effects in dogs, which is well supported by the veterinary literature. Since those papers, veterinarians have prescribed other NSAIDS such as Deramaxx or Meloxicam, in lieu of Piroxicam, because these newer selective Cox-2 inhibitors are associated with lower rates of side-effects, such as GI ulceration and upset. It is assumed (but not known) that the anti-tumor effects are due to the Cox-2 inhibition, so it is also assumed that cox-2 selective NSAIDs should work as well as piroxicam.
However, this remains to be supported in the veterinary literature. (Not enough studies), but Piroxicam (and possibly other NSAIDS) remains a reasonable palliative option with careful monitoring.

Famotidine (Pepcid AC)

Available in 10 and 20 mg tablets OTC

Stomach ulceration in humans is a prominent medical condition and there has long been pressure to develop effective and convenient ways to control it. Until relatively recently, we relied on simply neutralizing stomach acid by pouring alkaline solutions (i.e., Alka Seltzer, Tums, Rolaids, etc.) into the stomach. In fact, ulceration is a complicated process and there are many ways to address it.
Control of stomach acidity is an important factor in the treatment of stomach ulcers. Acid secretion is controlled by a hormone called gastrin (secreted in the presence of food and leading to secretion of stomach acid), acetylcholine (a neurotransmitter), and histamine (that same substance responsible for the unpleasant allergic effects of hay fever).
Famotidine is a special antihistamine, as are its cousins cimetidine (Tagamet HB) and ranitidine (Zantac). This class of antihistamine is not useful in combating familiar allergic symptoms (itching, sneezing, stuffy nose etc.) In allergy, histamine causes unpleasant effects by binding so-called H1 receptors. Famotidine, ranitidine, and cimetidine instead bind to histamine receptors in the stomach called H2 receptors.
Cimetidine was the first such H2 blocker available and each generation has brought about improvements in terms of fewer drug interactions and stronger effect. Famotidine is the longest lasting of the H2 blockers (usually one dose lasts 24 hours). Famotidine is 32 times stronger in its ability to inhibit stomach acid than is cimetidine and is 9 times stronger than ranitidine. A newer H2 blocker called nizatidine is now available that offers the additional advantages of especially rapid onset of action and some effect on normalizing stomach contractions as well.

Famotidine is currently available in an over-the-counter formulation making it highly convenient for pet owners to obtain (though obviously one should not consider using medications licensed for human consumption without specific instructions from one's veterinarian). Famotidine is especially useful for pets with chronic vomiting.

How This Medication Is Used

Famotidine is useful in any situation where stomach irritation is an issue and ulceration is a concern. It is often used in the treatment of Helicobacter infection, inflammatory bowel disease, canine parvovirus, ingestion of a toxin or medication that could be ulcerating (NSAIDs, like Metacam Meloxicam Peroxicam Duramaxx aspirin and others, for example), any disease involving protracted vomiting, or chronically in combination with medications which may have stomach irritating properties.
In diseases involving frequent vomiting or regurgitation, the esophagus (tube connecting the mouth and stomach) can be ulcerated by continuing exposure to vomit/stomach acid. Antacids are also helpful in this type of situation to reduce damage to the esophagus. Megaesophagus would be a condition where a long-acting antacid such as famotidine could be helpful in mitigating injury to the esophagus.

Side Effects

The H2 blockers as a group have a limited potential for side effects, hence their recent release to over-the-counter status.
There have been some reports of exacerbating heart rhythm problems in patients who already have heart rhythm problems, so it may be prudent to choose another means of stomach acid control in heart patients.
Interactions With Other Drugs
There are some drugs that are absorbed better in the presence of stomach acid (example: itraconazole). The dose of such drugs may require adjustment in the presence of famotidine.
Concerns and Cautions
The dose of famotidine may require reduction in patients with liver or kidney disease as these diseases tend to prolong drug activities.
It appears that famotidine is safe for use in pregnancy but should probably be avoided during lactation.

February 6, 2012

Immunizations and Boarding for Pets with Cancer

Pet Vaccinations and Cancer

Educate yourself.  Your veterinarian cannot make this decision for you, nor should they.  You are your pet’s guardian.  It is your responsibility to give them the best care you can by researching and carefully weighing your decisions about their healthcare.

Most have never been told the truth about vaccinations.  On the contrary, you are likely to get annual notices from your veterinarian that your pet is “due for their annual booster shots”.  The evidence against vaccinating, however, is overwhelming.  Most veterinarians just choose to ignore the research because they don’t want to lose the income from giving booster shots to all those animals each year.
Vaccinations represent a major stress to the immune system.  They can not only cause side-effects and allergic reactions, they also contribute significantly to long term chronic disease.  Chronic health problems frequently appear following vaccination including skin allergies, arthritis, leukemia, upper respiratory infections, irritable bowel syndromes, neurological conditions including aggressive behavior and epilepsy, auto-immune diseases and cancer.
It is more and more common to see cancer in dogs and cats under 5 years of age.  Autoimmune diseases are on the rise as well.  Our companions are suffering from generations of over-vaccination, which combined with inadequate nutrition, poor breeding practices and environmental stresses are leaving each generation more susceptible to congenital disorders and chronic disease.
Vaccinations do help prevent serious illnesses, but they should be used with restraint.  Before vaccinating, consider the risk.  If your pet is indoor only and does not go for walks and will never be exposed to unvaccinated animals, the risk of infection is low.  The decision about vaccinations is very individual and should be guided by your own research on the subject before you go to the veterinarian.
IF your pets go outside and you have rabies in your area, give a rabies vaccine at six months of age. (Legal requirements vary from state to state.)
Generally, vaccinations do not need “boosting”.  Studies have shown that a single vaccination for parvovirus, distemper and panleukopenia results in long-term protection from disease. Simple blood tests can determine if your companion’s antibody levels for parvovirus and distemper remain high enough to resist infection.  Next time your veterinarian suggests a booster shot, request the blood test first.  (Rabies may be required by law every three years.  Check the regulations in your state.)
Research about vaccinations for Bordetella, corona virus, leptospirosis or Lyme vaccines unless these diseases are endemic locally or at a specific kennel.

Never vaccinate a sick or weakened animal. Vaccinating an already compromised immune system is almost sure to compound the problem!

For pets that are due for rabies vaccinations that are required by law in their state, owners can request their veterinarian write a letter explaining why such a vaccination is medically contraindicated at the present time, along with a copy of records indicating that the pet had previously been current on vaccinations.

Pets that are receiving chemotherapy can be boarded. It is recommended that the boarding facility be provided contact information for the treating veterinarian in case of any symptoms or illnesses that develop while the pet is boarding that might require medical assistance. Similarly, the boarding facility should be informed that the pet is immunocompromised and that appropriate hygiene recommendations be followed, such as thorough hand washing before the pet is handled. Owners should discuss the upcoming boarding of their pet with the treating veterinarian, who may wish to modify the treatment schedule according to the boarding schedule.

Educate yourself.  Your veterinarian cannot make this decision for you, nor should they.  You are your pet’s guardian.  It is your responsibility to give them the best care you can by researching and carefully weighing your decisions about their healthcare.

February 3, 2012

What are the typical side effects of chemotherapy in dogs?

What are the typical side effects of chemotherapy in dogs?

Compared to people who receive chemotherapy, pet animals experience fewer and less severe side effects because we use lower doses of drugs and do not combine as many drugs as in human medicine. The normal tissues that typically are most sensitive to chemotherapy are the intestinal lining, the bone marrow (which makes red and white blood cells), and hair follicles.

Toxic effects to the gastrointestinal tract are responsible for decreased appetite, vomiting, and diarrhea. These effects may be mild, moderate, or severe. In most cases, these signs are mild and usually resolve on their own or with oral medication given at home. Although infrequent, some dogs (and cats) may develop severe diarrhea requiring hospitalization and fluid therapy. In many cases, the gastrointestinal side effects from chemotherapy are not seen on the day of treatment. They often occur 3 to 5 days later.

Suppression of the bone marrow by chemotherapeutic drugs may cause a drop in the white blood cell count, leading to increased susceptibility to infection. The infection usually comes from the animal's own body (such as bacteria normally found in the intestines, mouth, skin, etc.). Severe infections may require hospitalization for intensive supportive care, including intravenous fluid and antibiotics. When a chemotherapeutic drug is used that is known to have a high potential for bone marrow suppression, a complete blood count (CBC) is checked several days after the treatment. If the white blood cell count is low but your pet is feeling well, antibiotics are prescribed as a preventative measure. Subsequent doses of chemotherapy are adjusted based on the results of the CBC. Anemia (low red blood cell count) is often a complication of cancer but is rarely caused by the chemotherapy drugs used in veterinary medicine.
Hair follicle cell in dogs (and cats) that are wire-haired or non-shedding may be particularly susceptible to chemotherapy. Certain breeds of dogs, such as terriers and poodles, will experience variable amounts of hair loss. Hair loss often is most evident on the face and tail. Whiskers and the long hairs over the eyes often fall out in cats. The hair will regrow once chemotherapy is stopped, but may initially have a modest change in color or texture.

February 1, 2012

Budget chemotherapy for mast cell tumors in dogs

This is what I read somewhere. Normally this does not apply to nasal cancer, but you might know someone whose dog has this. PLUS, some non biopsied nasal cancers might have an uncommon form of mast cell tumor rather than adenocarcinoma, so the addition below might help symptoms.

Conventional Treatment
"Probably the best affordable option is a combination of prednisone and lomustine (CCNU). Prednisone is given daily, and lomustine is given every 3-4 weeks. CBCs do need to be monitored routinely. We would also add in daily an H2 blocker (eg. Pepcid /Tagamet) and an H1 blocker (antihistamine such as Chlortrimeton or Benadryl)."

Dose for Mast Cell Tumors and growths & epuli in a 55-75 lb. dog example

1 tab 200 mg. Tagamet (Cimetidine) and

1 tab 25 mg. Benadryl (Diphenhydramine) caplet

twice a day for 3 weeks. 


With dogs who are terminal, the treatment is continued for the rest of the dog's life.

Some people have increased the Benadryl to 2 tabs per dose with no negative side affects and increased the shrinkage.  Each dog is different and you should decide your treatment accordingly. Always talk to your vet. Even when he doesn't like what you want to do just because you 'read it on the internet'. 

Research this yourself - you will see.

How This Works:

  • Mast Cell tumors are comprised of T1 and T2 cancer cells. 

  • Tagamet & Benadryl are over-the-counter drugs that encapsulate the T1 & T2 cancer cells. 

  • Tagamet encapsulates T1 cells and Benadryl encapsulates T2 cells by cutting off the blood and oxygen supply. 

  • This causes the cells to die which shrinks the tumors and puts the cancer into remission.

  • You may see one tumor, but it is very likely that other tumors may exist in the body that you cannot see.

  • When a tumor is surgically removed, you are only removing the one you can see.
Here are some dog owner who said it helps