Not just Holistic, but how to use E: All of the Above!

I made this blog because I did tons of research on success stories and research worldwide and used it on my dog with nasal cancer named Lucy. So, now my hobby is molecular biology. The treatment uses combination of health store supplements, some prescription meds, diet changes, and specific Ayurvedic and Chinese medicinal herbs. I just wanted her to have a better quality of life. I thought this combination of E: All the Above (except no radiation or chemo and surgery for this cancer was not an option) would help that for sure, but it actually put her bleeding nasal cancer in remission!
My approach to cancer is about treating the whole animals biologic system. But I do hate the word 'Holistic'. Sounds like hoo hoo. This is science based, research based data and results of using active herbal compounds that happen to be readily available and common. Some call it Nutriceuticals. Others may call it Orthomolecular cancer therapy. Or Cancer Immunotherapy.
I FEEL DIVERSITY IN TREATMENT IS KEY:
-Slow cancer cell reproduction
-Make cancer cells become easier targets for the immune system
-Kill the cancer cells
-Rid the cancer cells
-Remove the toxins it produces
- Stimulate and Modulate the immune system
-Control secondary symptoms like bleeding, infection, inflammation, mucous, appetite, or pain for a better feeling animal
-Working with your vet for exams and prescriptions that are sometimes needed when conditions are acute.
Just by using a multi-modal treatment approach that is as diverse in attack as possible. Both conventional and natural.
The body conditions that allowed it to develop in the first place must be corrected. If caught early enough, like with Lucy, this ongoing maintenance correctional treatment is all that was required at this point to achieve, so far, more than 10 TIMES the life expectancy given (more than 60 months) after diagnosis WITH remission. I did not use radiation or chemotherapy or surgery.
I hope this cancer research can help your dog as well.

My Lucy

My Lucy
In Loving Memory my Lucy December 2016
CURRENT STATUS - It was for more than 5 YEARS after Lucy was diagnosed by biopsy in March 2011 with nasal cancer that she lived. And she was in remission for 4 of 5 years using no radiation or chemo! Now multiply that by 7 to be 35 years extended!! She was 12.5 years old - equivalent to almost 90 human years old. She ended her watch December 1, 2016. I miss her so much.

April 30, 2014

Sixty-two percent of chemotherapy drugs come from


"Sixty-two percent of chemotherapy drugs come from natural products, and plants have been the basis of almost every new class of medication," Gary says. "It makes sense that these plants can act as anticancer agents."


  "In their exhaustion and desperation, they were trying to find an alternative treatment that was not so harsh," says Cohen, who often prescribed herbs to be prepared as teas to ease the side effects of chemo and hormone therapy. But the patients' oncologists, says Cohen, discouraged them from trying anything new. "They'd say Chinese medicine was quackery and that there was no evidence it worked," he says. Still, Cohen observed that many of the women to whom he gave Chinese herbs, including Ban Zhi Lian, responded well to the herbs and even experienced a relatively good quality of life. "At first I chucked it to luck," he says. "But then you see it's not just luck. And then you ponder why."



Case Reports I found to give some examples:
(Case reports are provided to have a better understanding of the product. Please be aware that the info was received from acupuncturists/ Chinese medicine doctors and was not reviewed by FDA. Drs. Gu from California and Lei from Arkansas contributed to the cases).†
1. Female breast cancer patient, 45 years old. Blood test indicates a cancer cell index was as high as 22. Patient came to my office for TCM treatment because she does not want to go through surgery and chemotherapy treatment. I prescribed Tumoclear tablets for her to take orally and provided acupuncture and Qi-gong treatments. Her tumor was reduced in size significantly and the cancer cell index went down from 22 to 8. She has not undergone the excision surgery to date. Her condition is under the control completely.†
2. Late stage lung cancer patient, Female, 70 years old. Patient was diagnosed to have only 3-month time to live by Western medicine doctors. She had to take morphine to reduce the agonizing pain but with unsatisfactory results. After visiting our place, taking Tumoclear tablets and receiving acupuncture and Qi-Gong treatments, she reported her pain was reduced greatly. Tumoclear does have the analgesic and stabilizing effects. The patient eventually died after 9 months. Her family was grateful that her pain was reduced and she passed away very peacefully.†
3. Male patient, with metastatic Nasopharyngeal Carcinoma spreading to the brain. He was diagnosed by Western medicine doctors to have a 6-month survival time. Prescribed a large dose of Tumoclear from the start of the treatment. It has been more than two years since and his cancer is under control. He has been taking Tumoclear continuously under my supervision.†
4. Female patient, 20 years old at the time of visit, had Pharyngeal cancer. Patient had gone through chemotherapy but the cancer relapsed. She had a whole body edema, accompanied by the jaundice. Prescribed Tumoclear at large doses from the start of the treatment in conjunction with Guang Ci Tang’s Qin Dan Hua Shi Pian. Also provided acupuncture and Qigong treatments. Now at age of 24, her cancer is completely under control.†
5. Male, 45-year old, with pancreatic cancer. He had gone through chemotherapy treatment for approximately half a year without achieving apparent results. The size of the tumor was not reduced and at about 1.5cm. After coming to my clinic, she had since stopped the chemotherapy. Prescribed Tumoclear and Reishi mushroom (Ganoderma japonicum) in conjunction with acupuncture treatment. After three weeks treatment, the tumor had been reduced in size from 1.5cm to 0.3cm.†
6. Female, 55 years old, with metastatic lung cancer spreading to the cerebrum. She did not undergo chemotherapy or radiotherapy and instead chose to receive TCM treatment at my clinic. Prescribed Tumoclear and Reishi mushroom (Ganoderma japonicum) in conjunction with acupuncture treatment. After five weeks treatment, the brain tumor had disappeared from a size of 0.9cm at the onset.†



References
  • 1. Zhang Y. et al., Studies on Parmacology of Sarcandra glabra. Chinese Journal of the Practical Chinese with Modern Medicine, 2006 19:1839
  • 2. Zhu Y. et al., Journal of Emergency in Traditional Chinese Medicine. 2006 (5):533
  • 3. Carr C., Can Ancient Herbs Treat Cancer? Time 2007 Oct 15. Link
  • 4. Normile D., The New Face of Traditional Chinese Medicine, Science 2003 299:188.
  • by X. Li, Ph. D. (credentials)

I buy most of the stuff from Swanson Vitamins. They are cheaper, in capsules for dosage changes, and carry almost everything I give to Lucy except for the Chinese Herbs Stasis Breaker prescription, and the Low Dose Naltrexone prescription. Here is a $5 off coupon link I found

March 28, 2014

Soy-Derived Isoflavones like GENISTEIN Inhibit the Growth of Canine Cancers



Soy May Aid In Treating Canine Cancers
Apr. 11, 2009 — Researchers at North Carolina State University are looking to soy as a way to make traditional canine cancer therapy more effective, less stressful for the dog and less costly for the owners.

Dr. Steven Suter, assistant professor of oncology, and NC State colleagues studied genistein - a molecule found in soy that has been shown to be toxic to a wide variety of cancer cells in humans - to determine whether it would also inhibit the growth of canine lymphoma cells.
The researchers found that a commercially available form of genistein called GCP was effective in killing canine lymphoid cells in a laboratory setting, and that GCP is "bioavailable" in canines - meaning it is absorbed into the bloodstream where it can affect cancer cells in the body. The researchers hope that their findings will lead to the use of GCP for their canine patients in conjunction with traditional cancer treatments like chemotherapy.
The researchers' findings were published in Clinical Cancer Research.
"Humans have been using soy in conjunction with traditional chemotherapy for some time as a chemo potentiator," Suter says. "This means that the GCP makes the chemotherapy work more efficiently and faster, which translates to less stress on the patient and less money spent on chemotherapy."
Since dogs absorb GCP in much the same way that humans do, Suter hopes that veterinarians will be able to offer this therapy to canine patients in the near future.
"Since GCP is a dietary supplement, it is harmless to patients," he adds. "Plus it's inexpensive and easy to administer in a pill form. There's really no downside here."


Soy-Derived Isoflavones Inhibit the Growth of Canine Lymphoid Cell Lines

-GENISTEIN supplements ( google it as canine lymphoma genistein and see what comes up). Genistein is an isoflavone extracted from soybeans. If you google it you'll find page after page of promising research -- especially on lymphoma and t-cell lymphoma. Among other things it caused the death of cancer cells without harming healthy ones. (Something chemo or radiation DON"T do)
I found one source so far that is pure genistein costs alot but it is pure and likely near what researchers use due to dosage and pureness
Swanson now carries one. Yay! Cheaper!




Here is one article:


  1. Vahbiz Jamadar-Shroff1,
  2. Mark G. Papich2 and
  3. Steven E. Suter1
+ Author Affiliations


  1. Authors' Affiliations: Departments of 1Clinical Sciences and 2Molecular and Biomedical Sciences, North Carolina State College of Veterinary Medicine, Raleigh, North Carolina

  1. Requests for reprints:
    Steven E. Suter, North Carolina State College of Veterinary Medicine, 4700 Hillsborough Street, CVM Research Building #308, Raleigh, NC 27606. Phone: 919-513-0813; Fax: 919-513-7301; E-mail: 

Abstract

Purpose: This study aimed to evaluate the in vitro effects of genistein, both pure genistein and a commercially available form of genistein called Genistein Combined Polysacharride (GCP), against two canine B-cell lymphoid cell lines and determine the oral bioavailability of GCP when fed to normal dogs.

Experimental Design: The in vitro effect of genistein and GCP was evaluated using cell proliferation and apoptotic assays. The IC50 of both compounds was determined using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) cell proliferation assay and propidium idodide staining. Apoptosis was evaluated using Annexin V staining, caspase 3 and 9 staining, and DNA laddering. Cell cycle analysis and Bcl-2/Bax ratios were also examined. An initial dose escalating pharmacokinetic study was used to determine if therapeutic serum levels of genistein could be reached with oral dosing of GCP in normal dogs.

Results: The 72-hour in vitro IC50 of genistein and GCP against the GL-1 and 17-71 cells were both 10 μg/mL and 20 μg/mL, respectively. GCP led to cell death in both cell lines via apoptosis and treated cells exhibited increased Bax:Bcl-2 ratios. The serum concentrations of genistein in normal dogs given increasing oral doses of GCP did not reach the 72-hour in vitro IC50 in a dose escalation study.

Conclusions: The results of these studies support the notion that canine high-grade B-cell lymphoma may represent a relevant large animal model of human non-Hodgkin's lymphoma to investigate the utility of GCP in chemopreventive and/or treatment strategies that may serve as a prelude to human clinical lymphoma trials.

Translational Relevance

Canine lymphoma has historically been considered an excellent animal model of a variant of human non-Hodkin's lymphoma called diffuse, large B-cell lymphoma. Dogs are large, long-lived animals that are evolutionarily more closely related to humans than rodents; therefore, they represent an accessible, spontaneous population of high-grade lymphomas occurring in immunocompetent animals. Based on a large body of human literature documenting the antiproliferative effects of genistein, we hypothesized that genistein would also have in vitro activity against canine lymphoid cell lines and perhaps in vivo activity in canine lymphoma patients in either chemopreventive or treatment protocols. The results presented here support our hypothesis that genistein has significant in vitro antiproliferative activity against two well-established canine B-cell lines, mirroring human cell line data. Additionally, we developed an extremely sensitive high-pressure liquid chromatography–based assay to detect plasma genistein in dogs fed a commercially made, highly bioavailable form of genistein called Genistein Combined Polysacharride (GCP). With this assay, we were able to show that genistein in GCP can be absorbed by canine gut enterocytes, which leads to detectable genistein plasma levels. These initial studies with GCP lay the groundwork for future studies in the setting of canine lymphoma with findings that may be directly applicable to human diffuse large B-cell lymphoma. 

Genistein (4, 5, 7-trihydroxyisoflavone) is a readily available isoflavone found in soy-based products. Epidemiologic studies indicate that consumption of soy-containing diets is associated with a lower incidence of many human tumors (1, 2). Genistein has been identified as an inhibitor of various protein tyrosine kinases that play a role in cell growth and apoptosis, including camp-responsive element-binding protein (3), signal transducers and activators of transcription (4), members of the fork-head-related transcription factors (5), and nuclear factor κB (NF-κB; ref. 6). At pharmacologic concentrations genistein's recorded activities also include topoisomerase I and II inhibition (7), antioxidant activity (8), induced differentiation (9), and deregulation of mitochondrial membrane pore permeability (10). 

Genistein's effects on various human solid cancer cell lines have been extensively studied (11). Although the precise molecular mechanisms responsible for these activities are not clearly understood, the compound can inhibit cancer cell growth (12, 13), induce apoptotic cell death with cell cycle arrest at G2-M phase, and inhibit angiogenesis (14). Genistein causes epigenetic changes in mouse prostate (15) and up-regulates mRNA expression of the BRCA1 tumor suppressor gene during mammary tumorigenesis (16). The compound also inhibits DNA methyltransferase and reverses the methylation status, with concomitant reexpression, of the p16INK4a, RARb, and MGMT genes in human esophageal squamous cell carcinoma and prostate cell lines (17).

Genistein is also active against human lymphoid neoplasia (18, 19). Genistein induces apoptosis via mitochondrial damage in T lymphoma cells (20) and via Akt signaling in anaplastic large-cell lymphoma (21). The molecule also reduces NF-κb in T lymphoma cells via caspase-mediated cleavage of Iκβα (22). Finally, when included into a CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) lymphoma protocol, genistein has growth modulatory effects, via G2-M arrest and decreased NF-κb binding, in a diffuse large B-cell lymphoma xenograft setting (23). 

Natural and synthetic genistein glycosides are not easily absorbed across enterocytes in humans and cats (24, 25). Genistein Combined Polysacharride (GCP), a commercially available form of genistein (26), is a complex mixture produced by fermentation of soybean extracts with a mushroom mycelia (Ganoderma lucidum) culture that contains approximately 40% isoflavones. Fermentation deglycosylates soy isoflavones, producing aglycone isoflavones that are highly absorbable across the gut lumen (27). GCP has documented in vitro and in vivo effects on a wide variety of human cancers (28, 29). 

Case reports show complete regression of T3 prostate cancer following treatment with GCP (7); and supplementation with GCP prevented recurrence of transitional cell carcinoma (TCC) of the bladder (10).

Canine high-grade B-cell lymphoma, which is similar phenotypically and biologically to the most common variant of human non-Hodgkin's lymphoma called diffuse large B-cell lymphoma, is one of the most common malignant tumors of dogs (up to 25% of all cancers) and it is the most common hematopoietic tumor of the dog (83%; ref. 30). The median survival time of canine B-cell lymphoma patients treated with CHOP or L-VCAP (asparaginase, vincristine, cyclophosphamide, adriamycin, prednisone)-based protocols is 12 to 14 months, with an overall cure rate of <10% (31). Dogs are evolutionarily more closely related to humans than rodents and are large, long-lived animals; therefore, canine B-cell lymphoma represents an excellent model to investigate novel therapeutics and treatment strategies that may have direct applicability to the human disease (32). 

Based on the similarity between canine B-cell lymphoma and human diffuse large B-cell lymphoma, we hypothesized that genistein would inhibit the cell growth of two well-established canine lymphoid B-cell lines. We show that genistein induces cell death via apoptosis at concentrations similar to those reported in the human literature. We also present our preliminary findings of the oral absorption of GCP in domestic dogs.



Soy-derived isoflavones inhibit the growth of canine lymphoid cell ...
by V Jamadar-Shroff - 2009 - Cited by 17 - Related articles
Feb 15, 2009 - EXPERIMENTAL DESIGN: The in vitro effect of genistein and GCP was ... the notion that canine high-grade B-celllymphoma may represent a ...










**I will be starting genistein on Lucy's cancer on about 4/1/2014.  She was diagnosed in 4/2011 and has been taking the Tippner Protocol. I am adding a few new things because while she was in remission using only the pills on the Tippner cancer protocol, she has become stuffy again on the left side. Cancer can adapt and so must the protocol if needed. I will be adding genestein, luteolin, and apigen. I will have a research post on the luteolin and apigen soon.  The GCP version of genestein, I am still looking for a source.
Swanson now carries one. Yay! Cheaper!





I buy most of the stuff from Swanson Vitamins. They are cheaper, in capsules for dosage changes, and carry almost everything I give to Lucy except for the Chinese Herbs Stasis Breaker prescription, and the Low Dose Naltrexone prescription. Here is a $5 off coupon link I found

March 11, 2014

Xin Yi San for Mucous Mucus and What Snot



I got some new Chinese herbs, Xin Yi San a nasal decongestant,  to help relieve some of her mucous symptoms she has redeveloped with her nasal cancer. She is somewhat stuffy on her left side.  She had been in complete remission since 8/1/2011 on just the Tippner Protocol.
She starts Xin Yi San today 2 capsules per day 03/10/2014. I will note changes.


The chinese herbs she was given are below.  (She takes alot of other things as well)  These aren't regular herbs that you can purchase on the internet, they have to be prescribed by a licensed Chinese herbalist. Yup. 

Here is a lookup for vets in your area that use and prescribe them:
https://www.tcvmherbal.com/   left middle of page

If you cannot fnd a vet anywhere near you in the above vet pharmacy database-
 If your vet is not familiar with this veterinary herbal pharmacy, tell your vet that they do patient consults for free. But you still actually have to get your vet to order them for you.


Stasis Breaker to shrink the tumor - taken since 4/1/2011

Wei Qi Booster to boost immunity - taken since 4/1/2011

Xin Yi San a nasal decongestant - starts 4/10/2014

Ok for dogs and humans and horses and cats according to google:

http://books.google.com/books?id=vH6igOcDAZgC&pg=PT732&lpg=PT732&dq=xin+yi+san+for+dogs&source=bl&ots=Q1pn4xA5S7&sig=zSYbeMxBV88SrgL2eC5IQZkbb_c&hl=en&sa=X&ei=WVYfU6DCIIaGogSI2oK4DQ&ved=0CDgQ6AEwAw#v=onepage&q=xin%20yi%20san%20for%20dogs&f=false

http://lexysfight.blogspot.com/2012/11/chinese-herbs.html

http://brenewed.com/healthy-living/beaus-holistic-anti-cancer-lifestyle

http://www.justanswer.com/pet-cat/31afb-11-year-old-cat-sinus-congestion-type-symptoms.html

http://www.tcvmherbal.com/store/topFormula.asp?cid=6






I buy most of the stuff when possible from Swanson Vitamins. They are cheaper, in capsules for dosage changes, and carry almost everything I give to Lucy except for the Chinese Herbs Stasis Breaker prescription, and the Low Dose Naltrexone prescription. Here is a $5 off coupon link I found

February 26, 2014

New Less Invasive Option Being Tested For Dog Nasal Cancer - Freeze It!




The most common symptoms of nasal tumors in dogs are snorting sounds while breathing, nasal discharge, and nosebleeds.
The Typical vet treatment for nasal tumors involves radiation:
The mean survival time, after radiation, is 12-14 months. Side-effects of radiation treatments often impact a dog’s eyes and mouth as well. 4 months if zero treatment.
Michele Steffey, DVM, Dipl. ACVS, assistant professor of small animal surgery at University of California-Davis, School of Veterinary Medicine, is testing a new treatment called “transnare cryoablation.”
Essentially, she is using extreme cold to freeze and remove the tumor tissue.
Transnare cryoablation is considered less invasive that traditional treatments because it does not require any incisions. In addition, Steffey’s team can make several passes with the freezing probe while the pet is under anesthesia just once. Depending upon the specific case, some dogs may require additional sessions later.
For example, a 9-year-old chocolate Lab named Barkely had been in treatment for adenocarcinoma for a year when he became a patient of Steffey’s. The good news is that nasal adenocarcinoma often grows only where it begins without rapidly spreading to other areas of the body, such as the lungs or lymph nodes.
Barkely’s tumor stretched from the tip of his nose all the way to the back of his nasal cavity. While Barkely had some invasion from the left to the right side of his nose, the tumor had not broken through the cribriform plate, a bone that separates the nasal cavity from the brain.
In March 2013, while under anesthesia, Barkely received four consecutive treatments with the cryoprobe in about 45 minutes. He had a few nosebleeds afterwards, but Steffey says that’s to be expected.
Barkely’s four-month recheck CT scan showed no evidence of nasal tumor regrowth and no evidence that the cancer has spread to his lungs or lymph nodes.
The clinical trials of this new procedure are just beginning, so it’s hard to know how long these results may last. So far, things look promising.
Steffey says, “All types of nasal tumors may be enrolled in the study, and we will follow their outcome in order to eventually make more specific recommendations as needed. However, just like other local therapies for cancer (radiation, surgery), there may be anatomic or other limitations to safe administration of the treatment in an individual patient, and that decision can only be made on a case-by-case basis.”
ALSO:
Image-guided transnasal cryoablation of a recurrent nasal adenocarcinoma in a dog.

Abstract
PMID:


"We took our dog to UC Davis' soft tissue department.  Dr. Michelle Steffey saw her on January 23rd and determined the nasal cancer had not yet (operative word) crossed the brain barrier and therefore she was a candidate for Cryotherapy.  They kept her a couple of days before releasing her after the procedure.  The next four weeks she sneezed out, literally blew out black, sticky, smelly chunks and had a continuous pinkish brown nasal discharge.  I continued the organic cooking, the Pepsid A/C , Piroxicam (9mg), fish oil and chinese herb (Yunnan Baiyo, to prevent nose bleeds).  
"The cost:  pretty much depicted in the study info but it ran $1000 for the CT scan they had to do because it is "layered", different than what most local vets can do.  This past recheck cost us $328.  However, there were "extra" charges, such as medication (piroxicam, pain meds post treatment, various blood workups, anesthesia, boarding for 3 days" which added another approximate $900 to our first bill. You must also factor in hotels (we stayed at the crappy EconoLodge on D Street (about somewhat under $100 night after taxes), but it was a great environment for walking dog) and the hotel, the rental car. Rental car cost us $350 this last time but hotels were about the same.  Food, this time around for the 2 of us was about $100 over a 3.5 day period (2 adults and, of course dog). Plus airfare for non area people."


16 (yes you read that right) radiation treatments over three weeks
Each one requiring anesthesia



New Less Invasive Option Being Tested


Steffey explains, “The cryoprobe is basically a large needle that is closed at the tip. Inert gasses – argon and helium – are cycled through the cryoprobe to control the temperature and vented back through the system, so the patient is never directly exposed to the gasses. The argon is the gas that causes the drop in temperature around the probe due to the expansion of the gas (Joule-Thompson effect) within the probe. We take the temperature down to about -60 to -80 degrees Celsius to kill the tumor.”










 2011 Jun;52(6):329-33. doi: 10.1111/j.1748-5827.2011.01071.x.
An eight-year-old female spayed Airedale terrier with rapid recurrence of a nasal adenocarcinoma following image-guided intensity-modulated radiation therapy (BLOGGER NOTE - MEANING THE RADIATION DIDN'T WORK) was treated with transnasal, image-guided cryotherapy. Ice ball size and location were monitored real-time with computed tomography-fluoroscopy to verify that the entire tumour was enveloped in ice. Serial computed tomography scans demonstrated reduction in and subsequent resolution of the primary tumour volume corresponding visually with the ice ball imaged during the ablation procedure. Re-imaging demonstrated focallysis of the cribriform plate following ablation that spontaneously resolved by 13 months. While mild chronic nasal discharge developed following cryoablation, no other clinical signs of local nasal neoplasia were present. Twenty-one months after nasal tumour cryoablation the dog was euthanased as a result of acute *haemoabdomen*. Image-guided cryotherapy may warrant further investigation for the management of focal residual or recurrent tumours in dogs, especially in regions where critical structures preclude surgical intervention.

*NOTES: Hemoabdomen*, defined as the accumulation of blood within the peritoneal cavity, is a relatively common finding in dogs but rare in cats. The underlying cause of hemoabdomen can be either traumatic or spontaneous. The most common cause of traumatic hemoabdomen is a motor vehicle accident, but penetrating trauma can also result in abdominal bleeding. (Odd if the dog above also had yet another cancer!?)
Spontaneous hemoabdomen is caused by neoplasia 80 percent of the time in dogs but only 46 percent of the time in cats. The spleen is the most common organ in both species to develop neoplasia, and hemangiosarcoma is the most common diagnosis. Regardless of the cause, intra-abdominal hemorrhage can be life-threatening. 

© 2011 British Small Animal Veterinary Association.
21627662
[PubMed - indexed for MEDLINE]

  She had her four-week checkup on Monday and the tumor is g-o-n-e.  Gone!  Gone!  The freeze worked.  Within a week we suspected success because Sam could once again breathe out of her left nostril.  
  We realize that there is no "cure" for nasal cancer.  Nevertheless, the tumor is gone -- it does not mean it won't come back -- but it is gone and we will continue to keep our eyes on things.
  I will also say there were no side effects, it is a better treatment option than radiation (in my opinion) we do not need her on chemotherapy drugs, yet the cost is less than chemo and probably less than radiation therapy."







LINK TO CALIFORNIA UC DAVIS VET TRIAL FOR THIS UCD – Nasal Tumor: Transnare Cryoablation of Nasal Tumors Study Trials
PROCEDURE
THIS IS A PARTIALLY FUNDED STUDY. Dog owners participating in this study will be given special financial considerations. The cost of cryoablation procedure (excluding the costs of general anesthesia) will be covered by the study (an approximately $4000 benefit to the client) but standard medical costs (hospitalization, medications, etc) are the responsibility of the client. There will be no charge for the study rechecks at 1 month, 4 months, and 8 months. You will be financially responsible for the charges associated with the clinical care of your dog beyond the stipends provided. Owner Responsibilities: The owner will be responsible for the individualized costs of the patient’s care at the time of the treatment (anesthesia, hospitalization, medications, other individualized diagnostic tests needed to ensure the patient is safe for the procedure), and for scheduling recheck appointments post-treatment and keeping those appointments as required by protocol. Owners also have the responsibility to cover the cost of the initial examination, pre-treatment workup, pre-treatment CT scan, and any additional diagnostic tests needed to determine their dog’s eligibility for the study, and medications prescribed. Initial Evaluation for Participation: All dogs must be examined by a VMTH oncology, internal medicine, radiation oncology service or soft tissue surgery veterinarian, and require the baseline evaluations described above at the owners expense before a dog can be considered for enrollment in the trial.Procedures: Cryoablation procedure is a minimally invasive procedure performed under general anesthesia. Special cryoablation needles are inserted through the nostrils, and freezing sufficient to kill the tumor is applied.
 - I found a quote:




I buy most of my pill stuff from Swanson Vitamins. They are cheaper, in capsules for dosage changes, and carry almost everything I give to Lucy except for the Chinese Herbs Stasis Breaker prescription, and the Low Dose Naltrexone prescription. Here is a $5 off coupon link I found