Anti-angiogenic Drugs
For cancer cells to divide and become solid tumors they are dependent upon the formation of blood vessels, a process known as angiogenesis, that will provide blood flow with oxygen and nutrients to the developing tumor. Many cancer cells excrete molecules into the surrounding tissues that stimulate the formation of new blood vessels. Based on these observations, the novel idea of inhibiting tumor growth by cutting off blood supply to the tumor was developed. Natural and synthetic inhibitors of vascular formation, known as anti-angiogenic drugs, have been purified, formulated and assessed for their abilities as anti-tumor agents. Such drugs include angiostatin, thrombospondin, and endostatin. In preclinical animal studies, anti-angiogenic drugs have been found to significantly inhibit tumor growth and in some instances produce tumor regression.
Anti-angiogenic Drugs in the Treatment of Canine Cancer
Many of these anti-angiogenic drugs are in the early stages of clinical development for treatment of human cancers. Dog-related News Article: "Anti-angiogenesis: Perhaps a new way to address cancer"
Applications of Anti-angiogenic Drugs in the Treatment of Cancer
Antiangiogenic strategies and agents in clinical trials.
Rosen L.
Angiogenesis: new targets for the development of anticancer chemotherapies.
Gourley M, Williamson JS.
Angiogenesis and Cancer Control: From Concept to Therapeutic Trial.
Brem S.
Novel cancer therapies: more efficacy, less toxicity and improved organ preservation.
Joensuu H. ***For a more complete listing, enter the following format of search terms in the PubMed search window: antiangiogenic-therapy AND cancer
Many health food store supplements have Anti-angiogenic properties. Take a look at Lucys pill list I give her.
Plus a few antibiotics like Doxycycline and NSAIDS like Metacam/Meloxicam/Peroxicam show these properties. This is called the NAVY protocol. Or Metronomic Protocol when each given on alternating days.
This is about using every non radiation non chemo treatment for cancer. All research and results will be posted. Nasal cancer in dogs. Canine nasal cancer.
Not just Holistic, but how to use E: All of the Above!
I made this blog because I did tons of research on success stories and research worldwide and used it on my dog with nasal cancer named Lucy. So, now my hobby is molecular biology. The treatment uses combination of health store supplements, some prescription meds, diet changes, and specific Ayurvedic and Chinese medicinal herbs. I just wanted her to have a better quality of life. I thought this combination of E: All the Above (except no radiation or chemo and surgery for this cancer was not an option) would help that for sure, but it actually put her bleeding nasal cancer in remission!
My approach to cancer is about treating the whole animals biologic system. But I do hate the word 'Holistic'. Sounds like hoo hoo. This is science based, research based data and results of using active herbal compounds that happen to be readily available and common. Some call it Nutriceuticals. Others may call it Orthomolecular cancer therapy. Or Cancer Immunotherapy.
My approach to cancer is about treating the whole animals biologic system. But I do hate the word 'Holistic'. Sounds like hoo hoo. This is science based, research based data and results of using active herbal compounds that happen to be readily available and common. Some call it Nutriceuticals. Others may call it Orthomolecular cancer therapy. Or Cancer Immunotherapy.
I FEEL DIVERSITY IN TREATMENT IS KEY:
-Slow cancer cell reproduction
-Make cancer cells become easier targets for the immune system
-Kill the cancer cells
-Kill the cancer cells
-Rid the cancer cells
-Remove the toxins it produces
- Stimulate and Modulate the immune system
-Control secondary symptoms like bleeding, infection, inflammation, mucous, appetite, or pain for a better feeling animal
-Working with your vet for exams and prescriptions that are sometimes needed when conditions are acute.
Just by using a multi-modal treatment approach that is as diverse in attack as possible. Both conventional and natural.
The body conditions that allowed it to develop in the first place must be corrected. If caught early enough, like with Lucy, this ongoing maintenance correctional treatment is all that was required at this point to achieve, so far, more than 10 TIMES the life expectancy given (more than 60 months) after diagnosis WITH remission. I did not use radiation or chemotherapy or surgery.
I hope this cancer research can help your dog as well.
ARTICLE CATEGORIES
My Lucy
In Loving Memory my Lucy December 2016
CURRENT STATUS - It was for more than 5 YEARS after Lucy was diagnosed by biopsy in March 2011 with nasal cancer that she lived. And she was in remission for 4 of 5 years using no radiation or chemo! Now multiply that by 7 to be 35 years extended!! She was 12.5 years old - equivalent to almost 90 human years old. She ended her watch December 1, 2016. I miss her so much.
