Mediastinal T-cell Lymphoma in dogs
Mediasintal doesn't present with surface lumps -- the tumour
develops between the lungs and heart then spreads throughout the lymph system.
Usually given 3 - 6 weeks to live... 8 - 12 weeks best case without
any treatment by a vet with chemo for weeks.
Other B and T cell Lymphomas
Untreated dogs have an average survival time of 60 days.[14] Lymphoma with a histologic high grade generally respond better to treatment but have shorter survival times than dogs with low grade lymphoma.[6] Dogs with B-lymphocyte tumors have a longer survival time than T-lymphocyte tumors.[1] Mediastinal lymphoma has a poorer prognosis than other types, especially those with hypercalcemia.[
This is vet untreated but......
Actually most human lymphoma treatments are first tested on animals so it
isn't difficult trying to find references to canine lymphoma research and treatment options. I also tried to cross reference between
natural and regular medicine sites where possible. I tried to use my own common
sense, and my open my mind to new concepts as long as there
was enough research to back it up.
Differences in pills given for Lymphoma compared to Lucy nasal cancer so far in my re-analysis for this specific cancer:
-Lucy nasal cancer protocol includes mushroom based immune boosters (ie. Cordeceps, and a multi -mushroom variety) because while they may benefit most
cancer patients, they also trigger t-cells which may not be the best thing for T-cell lymphomas.
-GENISTEIN supplements ( google it as canine lymphoma genistein and see what
comes up). Genistein is an isoflavone extracted from soybeans. If you google it
you'll find page after page of promising research --
especially on lymphoma and t-cell lymphoma. Among other things it caused the
death of cancer cells without harming healthy ones. (Something chemo or
radiation DON"T do)
I found one source so far that is pure genistein costs alot but it is pure and likely near what researchers use due to dosage and pureness
-I also have Lucy on Melatonin--- Good for many cancers like hers. but NOT for lymphoma -- or
at least, evidence for leukemia and lymphoma patients is not complete, but early
evidence suggests it may be better for those cancers than the
patient. Therefore -- don't use that one.
-If there is no bleeding, you don't need the Yun Nan Bai Yao herbs.
-Do not give Bone Essentials- it is not needed for one and may be bad for elevated calcium level dogs. I do need to research this more.
In fact, there are other things on her list I also would not give for Lymphoma due to too much T-cell boosting that other cancers actually need so just for now give the below basics till more research is done to list specific for lymphoma :
I would say go with the IP6, Colostrum, the key Antioxidant Resveretrol, Flax Oil and Cottage Cheese snacks, a good Fish oil (Salmon) liquid added to meals, Milk Thistle for lymphatic drainage, Moducare, and Genestein. I get all these from swansonvitamins except that genestein from Luckyvitamin.
Keeping giving good human-quality food, warmed with warm water, and exercise(just get him to go outside for a bit at least) him every day. And be positive around your pet -- if you are depressed, they'll pick up on it and be down themselves. I think those are the basics.
http://en.wikipedia.org/wiki/Lymphoma_in_animals like dogs more info on Lymphoma in dogs
ip6 lymphoma dogs
milk thistle for lymphatic drainage
Moducare for lymphoma
Genestein info below
Soy-derived isoflavones inhibit the growth of canine lymphoid cell ...
www.ncbi.nlm.nih.gov/pubmed/19228730
by V Jamadar-Shroff - 2009 - Cited by 17 - Related articles
Feb 15, 2009 - EXPERIMENTAL DESIGN: The in vitro effect of genistein and GCP was ... the notion that canine high-grade B-cell lymphoma may represent a ...
GCP, a genistein-rich compound, inhibits proliferation and induces ...
www.ncbi.nlm.nih.gov/pubmed/19394691
by JL McCall - 2010 - Cited by 10 - Related articles
Apr 25, 2009 - Genistein combined polysaccharide (GCP), derived from soy bean extract, ... In three human and four canine lymphoid cell lines, GCP inhibited ... GCP may have clinical utility in the treatment of patients with lymphoma.
Soy Protein | VCA Animal Hospitals
www.vcahospitals.com/main/pet-health-information/article/.../571
Genistein is found in other plants as well, including red clover, and is one of the ... The potential benefits of soy proteins in dogs and cats are largely ... No similar products for the treatment of lymphoma in animals have yet been developed.
Soy May Aid In Treating Canine Cancers - Science Daily
www.sciencedaily.com/releases/2009/04/090408140210.htm
Apr 11, 2009 - Researchers are looking to soy as a way to make traditional canine cancer ... and NC State colleagues studied genistein - a molecule found in soy that has ... whether it would also inhibit the growth of canine lymphoma cells.
Genistein combined polysaccharide (GCP) is highly active in both ...
meeting.ascopubs.org/cgi/content/abstract/25/18_suppl/14126
by PC Mack - 2007
Genistein combined polysaccharide (GCP) is highly active in both human and canine lymphoma models. P. C. Mack, R. A. Burich, J. L. McCall, M. S. Kent, R. M. ...
Watson's Canine Lymphoma Blog
lovingwatson.blogspot.com/
Aug 18, 2009 - A blog about my dog Watson's fight with canine lymphoma. ... of oncology, and NC State colleagues studied genistein - a molecule found in soy ...
Genistein Combined Polysaccharide (GCP) is ... - Google Books
books.google.com/.../Genistein_Combined_Polysaccharide_GCP_is.html?...
Genistein Combined Polysaccharide (GCP) is Highly Active in Both Human and Canine Lymphoma Models. Front Cover. Jamie Lee McCall. University of ...
Soy-derived isoflavones inhibit the growth of canine ... - ResearchGate
www.researchgate.net/.../24026623_Soy-derived_isoflavones_inhibit_the_...
The serum concentrations of genistein in normal dogs given increasing oral ... the notion that canine high-grade B-cell lymphoma may represent a relevant large ...
GCP, a genistein-rich compound, inhibits ... - ResearchGate
www.researchgate.net/.../24360387_GCP_a_genistein-rich_compound_inhi...
In three human and four canine lymphoid cell lines, GCP inhibited ... in vitro efficacy, GCP may have clinical utility in the treatment of patients with lymphoma. 0 0.
Soy May Aid In Treating Canine Cancers
Apr. 11, 2009 — Researchers at North Carolina State University are looking to soy as a way to make traditional canine cancer therapy more effective, less stressful for the dog and less costly for the owners.
Dr. Steven Suter, assistant professor of oncology, and NC State colleagues studied genistein - a molecule found in soy that has been shown to be toxic to a wide variety of cancer cells in humans - to determine whether it would also inhibit the growth of canine lymphoma cells.
The researchers found that a commercially available form of genistein called GCP was effective in killing canine lymphoid cells in a laboratory setting, and that GCP is "bioavailable" in canines - meaning it is absorbed into the bloodstream where it can affect cancer cells in the body. The researchers hope that their findings will lead to the use of GCP for their canine patients in conjunction with traditional cancer treatments like chemotherapy.
The researchers' findings were published in Clinical Cancer Research.
"Humans have been using soy in conjunction with traditional chemotherapy for some time as a chemo potentiator," Suter says. "This means that the GCP makes the chemotherapy work more efficiently and faster, which translates to less stress on the patient and less money spent on chemotherapy."
Since dogs absorb GCP in much the same way that humans do, Suter hopes that veterinarians will be able to offer this therapy to canine patients in the near future.
"Since GCP is a dietary supplement, it is harmless to patients," he adds. "Plus it's inexpensive and easy to administer in a pill form. There's really no downside here."