Ashwagandha herbs effect on Cancer
Antioxidant properties
Researchers from Banaras Hindu University in Varanasi, India, have discovered that some of its chemicals are powerful antioxidants. They tested these compounds for their effects on rat brain and found an increase in the levels of three natural antioxidants — superoxide dismutase, catalase and glutathione peroxidase. They say, "These findings are consistent with the therapeutic use of ashwagandha as an Ayurvedic rasayana (health promoter). The antioxidant effect of active principles may explain, at least in part, the reported anti-stress, cognition-facilitating, anti-inflammatory and anti-aging effects produced by them in experimental animals, and in clinical situations."
Anti-anxiety herb
The roots of ashwagandha are used extensively in Ayurveda, the classical Indian system of medicine. In rodent studies the herb has been shown to reduce anxiety and have a positive effect on mood.
Antibacterial research studies
Antibacterial efficacy of Withania somnifera an indigenous medicinal plant against experimental murine salmonellosis.
Phytomedicine. 2005 Mar.
We evaluated the antibacterial activity of ashwagandha root and leaves, against pathogenic bacteria. Both aqueous as well as alcoholic extracts of the ashwagandha plant (root as well as leaves) were found to possess strong antibacterial activity against a range of bacteria including Salmonella typhimurium. Moreover, in contrast to the synthetic antibiotic (viz. chloramphenicol), ashwagandha extracts did not induce lysis on incubation with human erythrocytes, advocating their safety to the living cells. Finally, the antibacterial efficacy of the ashwagandha extracts isolated from plant (both root and leaves) was determined against experimental salmonellosis in Balb/C mice. Oral administration of the aqueous extracts successfully obliterated salmonella infection as revealed by increased survival rate as well as less bacterial load in various vital organs of the treated animals.
Blood sugar
One small study found ashwagandha root was able to reduce blood sugar and cholesterol levels, and had a diuretic effect.
Brain health
Ashwagandha is used in India to treat mental deficits in geriatric patients, including amnesia. Researchers from the University of Leipzig in Germany wanted to find out which neurotransmitters were influenced by the herb. After injecting some of the chemicals in ashwagandha into rats, they later examined slices of their brain and found an increase in acetylcholine receptor activity. The researchers say, "The drug-induced increase in acetylcholine receptor capacity might partly explain the cognition-enhancing and memory-improving effects observed in animals and humans."
A study done in 1991 at the Department of Pharmacology, University of Texas Health Science Center indicated that extracts of ashwagandha had GABA-like activity. This may account for this herb’s anti-anxiety effects.
A 2002 laboratory study indicates ashwagandha extract stimulates the growth of axons and dendrites. A 2001 study in rodents showed the extract had memory boosting ability. A 2000 study with rodents showed it to have anti-anxiety and anti-depression effects.
Cancer
Withaferin A is a potent inhibitor of angiogenesis (new blood vessel growth). Angiogenesis 2004.
Growth inhibition of human tumor cell lines by withanolides from ashwagandha leaves.
Life Sci. 2003 Nov 21.
The leaves of ashwagandha are used in the treatment of tumors and inflammation in several Asian countries. We have isolated twelve withanolides from the leaves of this species. Compounds were tested for their anti-proliferative activity lung, colon, central nervous system and breast human tumor cell lines. Withaferin A and its derivatives exhibited inhibitory concentrations. Viscosalactone B showed the 50% inhibition. Therefore, incorporation of ashwagandha in the diet may prevent or decrease the growth of tumors in human.
Diabetes and high blood sugar
Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root.
Indian J Exp Biol. 2000.
Hypoglycemic, diuretic and cholesterol lowering effects of roots of ashwagandha were assessed on human subjects. Six mild non insulin dependent subjects and six mild high cholesterol subjects were treated with the powder of roots of ashwagandha for 30 days. Decrease in blood glucose was comparable to that of an oral hypoglycemic drug. Significant increase in urine sodium, urine volume, significant decrease in serum cholesterol, triglycerides, LDL (low density lipoproteins) and VLDL (very low density lipoproteins) cholesterol were observed indicating that this plant is a potential source of hypoglycemic, diuretic and hypocholesterolemic agents.
Lymphoma
Anticarcinogenic activity of Withania somnifera Dunal against Dalton's Ascitic Lymphoma.
J Ethnopharmacol. 2004.
The effect of ethanolic extract of ashwagandha root against Dalton's Ascitic Lymphoma has been evaluated in Swiss albino mice. A significant increase in the life span and a decrease in the cancer cell number and tumour weight were noted in the tumour-induced mice after treatment. These observations are suggestive of the protective effect of ashwagandha extract in Dalton's Ascitic Lymphoma.
Nerve cell growth
Axon- or dendrite-predominant outgrowth induced by constituents from Ashwagandha.
Kuboyama T.. Neuroreport. 2002.
We previously reported that the methanol extract of Ashwagandha (roots of Dunal) induced dendrite extension in a human neuroblastoma cell line. In this study, we found thatcompounds isolated from the methanol extract enhanced neurite outgrowth in human neuroblastoma SH-SY5Y cells.
Nitric oxide production
Induction of nitric oxide synthase expression by ashwagandha in macrophages.
Iuvone T, Esposito G, Life Sci. 2003.
Ashwagandha may induce the synthesis of inducible nitric oxide synthase expression likely by acting at transcriptional level. The increased nitric oxide production by macrophages could account, at least in part, for its immune stimulating properties.
I give Lucy 1 capsule with her AM meal.
This is about using every non radiation non chemo treatment for cancer. All research and results will be posted. Nasal cancer in dogs. Canine nasal cancer.
Not just Holistic, but how to use E: All of the Above!
I made this blog because I did tons of research on success stories and research worldwide and used it on my dog with nasal cancer named Lucy. So, now my hobby is molecular biology. The treatment uses combination of health store supplements, some prescription meds, diet changes, and specific Ayurvedic and Chinese medicinal herbs. I just wanted her to have a better quality of life. I thought this combination of E: All the Above (except no radiation or chemo and surgery for this cancer was not an option) would help that for sure, but it actually put her bleeding nasal cancer in remission!
My approach to cancer is about treating the whole animals biologic system. But I do hate the word 'Holistic'. Sounds like hoo hoo. This is science based, research based data and results of using active herbal compounds that happen to be readily available and common. Some call it Nutriceuticals. Others may call it Orthomolecular cancer therapy. Or Cancer Immunotherapy.
My approach to cancer is about treating the whole animals biologic system. But I do hate the word 'Holistic'. Sounds like hoo hoo. This is science based, research based data and results of using active herbal compounds that happen to be readily available and common. Some call it Nutriceuticals. Others may call it Orthomolecular cancer therapy. Or Cancer Immunotherapy.
I FEEL DIVERSITY IN TREATMENT IS KEY:
-Slow cancer cell reproduction
-Make cancer cells become easier targets for the immune system
-Kill the cancer cells
-Kill the cancer cells
-Rid the cancer cells
-Remove the toxins it produces
- Stimulate and Modulate the immune system
-Control secondary symptoms like bleeding, infection, inflammation, mucous, appetite, or pain for a better feeling animal
-Working with your vet for exams and prescriptions that are sometimes needed when conditions are acute.
Just by using a multi-modal treatment approach that is as diverse in attack as possible. Both conventional and natural.
The body conditions that allowed it to develop in the first place must be corrected. If caught early enough, like with Lucy, this ongoing maintenance correctional treatment is all that was required at this point to achieve, so far, more than 10 TIMES the life expectancy given (more than 60 months) after diagnosis WITH remission. I did not use radiation or chemotherapy or surgery.
I hope this cancer research can help your dog as well.
ARTICLE CATEGORIES
My Lucy
In Loving Memory my Lucy December 2016
CURRENT STATUS - It was for more than 5 YEARS after Lucy was diagnosed by biopsy in March 2011 with nasal cancer that she lived. And she was in remission for 4 of 5 years using no radiation or chemo! Now multiply that by 7 to be 35 years extended!! She was 12.5 years old - equivalent to almost 90 human years old. She ended her watch December 1, 2016. I miss her so much.
